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when using FINA or DECA , can WINNY replace the dostinex ?

Nighthawkk said:
Winny doesn't lower prolactin, I believe it competes for the progesterone receptor thus blocking some of the negative effects of tren or deca. This is theory right now, I have yet to see studies done on the effects of stanazolol on circulating prolactin or progesterone.

Indeed you are right..I stand corrected...
 
The prgestins don't mediate their sides solely through the progesterone receptor, so antagonizing the PR via DHT-like compounds is inefficient/incomplete. The progestins, tren and nandrolone (and likely anadrol), have a anti-glucocorticoid activity. using them reduces endogenous cortisol production, and this is what causes a rise in prolactin levels. prolactin is anti-dopaminergic. however, test and DHT are pro-dopaminergic, so that's why using test with any of the progestins is recommended. Still, using a dopamine receptor agaonist like cabergoline is a good idea, as long as you're not lowering prolactin below reference ranges.

Additionally, the progestins can upregulate ER expression, so this is another indirect way that they mediate gyno formation. Using nolva can help but may not be sufficient.

Proviron would be a good AI to use during a progestin + test cycle, because Proviron is 1-methyl DHT, so has inherent anti progesterone abilities....it'll also act as an AI....it's also an androgen, so will reduce SHBG levels and increase bioavailable AAS %'s. Proviron + nolva + a low dose cabergoline regimen would be ideal IMO.
 
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