I had some pre-cheat-meal yesterday and day before (high fat meal) per Mr Spellwin's advice. I was expecting wet farts and trouser chili but had neither, I think you need to build up to a certain dosage to feel those effects.
Taking 1 pill with a cheat meal I can confirm does not cause any unpleasant sides, though I don't know if it blocked the alleged 30% dietary fat either.