I took glucosamin/chrondriton and I didnt notice a bit of difference. Its now post cycle for me, but I had some bad tendonitis in one elbow so I scored some pure MSM powder and am trying that, too soon to tell though. In the mean time aleeve seemed to help a lot, but I would not take it for long while using a 17-aa oral. Do a search for MSM, there was a pretty big thread on it not too long ago.