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I would like to see any solid research that it helps your hair grow. or prevents it from falling out. Its just an anti-fungal.......
why nizoral?
- Thread starter justwannagetsum
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so do it yourself...www.google.com
justwannagetsum
New member
so do it yourself
I dont need to. I think a lot of bros are wasting their funds....
I dont need to. I think a lot of bros are wasting their funds....
here you go:
Ketoconazole shampoo: effect of long-term use in androgenic alopecia.
Pierard-Franchimont C, De Doncker P, Cauwenbergh G, Pierard GE.
Department of Dermatopathology, University of Liege, Belgium.
BACKGROUND: The pathogenesis of androgenic alopecia is not fully understood. A microbial-driven inflammatory reaction abutting on the hair follicles might participate in the hair status anomaly. OBJECTIVE: The aim of our study was to determine if ketoconazole (KCZ) which is active against the scalp microflora and shows some intrinsic anti-inflammatory activity might improve alopecia. METHOD: The effect of 2% KCZ shampoo was compared to that of an unmedicated shampoo used in combination with or without 2% minoxidil therapy. RESULTS: Hair density and size and proportion of anagen follicles were improved almost similarly by both KCZ and minoxidil regimens. The sebum casual level appeared to be decreased by KCZ. CONCLUSION: Comparative data suggest that there may be a significant action of KCZ upon the course of androgenic alopecia and that Malassezia spp. may play a role in the inflammatory reaction. The clinical significance of the results awaits further controlled study in a larger group of subjects.
Ketoconazole shampoo: effect of long-term use in androgenic alopecia.
Pierard-Franchimont C, De Doncker P, Cauwenbergh G, Pierard GE.
Department of Dermatopathology, University of Liege, Belgium.
BACKGROUND: The pathogenesis of androgenic alopecia is not fully understood. A microbial-driven inflammatory reaction abutting on the hair follicles might participate in the hair status anomaly. OBJECTIVE: The aim of our study was to determine if ketoconazole (KCZ) which is active against the scalp microflora and shows some intrinsic anti-inflammatory activity might improve alopecia. METHOD: The effect of 2% KCZ shampoo was compared to that of an unmedicated shampoo used in combination with or without 2% minoxidil therapy. RESULTS: Hair density and size and proportion of anagen follicles were improved almost similarly by both KCZ and minoxidil regimens. The sebum casual level appeared to be decreased by KCZ. CONCLUSION: Comparative data suggest that there may be a significant action of KCZ upon the course of androgenic alopecia and that Malassezia spp. may play a role in the inflammatory reaction. The clinical significance of the results awaits further controlled study in a larger group of subjects.
thepunisher
New member
wow, good work
It helps prevent the synthesis of DHT in the scalp.
Per:
http://www.minoxidil.com/Ketoconazole%20Treatment%20Shampoo.htm
Per:
http://www.minoxidil.com/Ketoconazole%20Treatment%20Shampoo.htm
K
kronk
Guest
justwannagetsum said:
With all due respect, that was a very asinine and ignorant statement.
For the rest of the newbies and "ole"bies LOL out there that will see this before searching more, here is some information. Some great stuff has already been posted so far, and I am only posting this as further information.
Here is a link to the results of a 2 year study on the active ingredient in Nizoral:
http://www.hairlosssucks.com/download/nizoral.pdf
"Nizoral is an anti-fungal shampoo that kills the fungi that cause seborrhea and dandruff.
Groups of individuals have discovered that Nizoral (when used regularly) is a very useful alopecia treatment, once again it would appear that the role of a substance for the treatment of hair-loss is stumbled upon accidentally!
Nizoral contains a chemical called ketoconazole, it is known that when ketoconazole is ingested orally that it inhibits the binding of androgens to receptors in the body and this would include the binding of DHT to hair-follicle receptors.
However the use of oral ketoconazole is NOT recommended for many reasons, mainly because this method would present itself as a toxin and ultimately damage the liver. But topical ketoconazole (as contained in Nizoral shampoo) shows itself to have a "weak" anti-DHT binding affect in the scalp.
Furthermore positive results with Nizoral shampoo are often noted within a few weeks, whereas a pure anti-DHT affect may take a few months. It is therefore likely that Nizoral exhibits another method to its anti-hair-loss effect.
One such theory of Nizoral’s anti-alopecia effects may be on its activity upon sebum.
Sebum is a fatty substance that accumulates in the scalp around the hair follicles. It’s possible that the removal of sebum may help "unclog" the hair follicle and expose it to more nutrition from an improved blood supply, rather like unclogging a drain!
It is known that Nizoral can remove and reduce sebum deposits."
Yes, and kind of dissin a lot of bros including myself who have *used it and have not it during cycles* and know that it does help.
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