Aspartame is a dipeptide of two naturally occurring amino acids. Are you a phenylketonuric? If so,you would have a problem with any product containing significant amounts of l-phenylalanine. There is scant evidence against Aspartame, my Jesus freak sister hates all artificial sweeteners because Jesus didn't make them but she loves the Stevia...an all natural product which I was able to produce studies published in legitimate journals showing serious negative reactions in humans. Being able to produce a few studies doesn't prove anything.