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A double-blind, randomized study was conducted to determine the effect of a novel human pheromone formulation (Di-Dehydroepiandrosterone) on plasma blood pheromone levels and sociosexual behaviors in men in regard to women. Members of the group (n=84) had blood collected at the beginning and end of an 12 week period of the study along with a journal documenting sexual intercourse activity. Subjects were supplemented with Di-Dehydroepiandrosterone in a fragrance marketed under the trade name "pherlure" (n=43) or a placebo fragrance (n=41) for the 12 weeks. The subject group applied 2 sprays daily of the Di-Dehydroepiandrosterone added fragrance. The plasma pheromone levels increased in the Di-Dehydroepiandrosterone group by 22.6%, respectively, while levels decreased in the placebo group by 1.4%, respectively. The total journalized sexual intercourse activity levels increased in the Di-Dehydroepiandrosterone group by 62.4%, respectively, in contrast to the placebo group which increased by 2.8%, respectively. All comparisons were statistically significant (P<0.001). These findings suggest that daily supplementation with Di-Dehydroepiandrosterone significantly increases plasma blood pheromone levels and sociosexual behaviors.
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