True or False (T/DHT)

[Oceano]

As T declines, amount of DHT increases to compensate.

Is this true or a falsehood?

If you think it is true please state why and if you think it is false please state why.

 

[lanky]

in general,,, when testosterone is high so is DHT

as we age DHT actually decreases as well as testosterone

 

[Mavafanculo]

generally speaking, since d.h.t. is produced from test via interaction with 5-AR, lower test = lower dht.

I dont recall reading anywhere about an inverse relationship between test levels and 5-AR levels which would cause what you are asking about.

 

[Tatyana]

generally speaking, since d.h.t. is produced from test via interaction with 5-AR, lower test = lower dihydrotestosterone.

I dont recall reading anywhere about an inverse relationship between test levels and 5-AR levels which would cause what you are asking about.

Exactly, test is produced in the testicles and to a lesser extent in the adrenal glands.

5 alpha reductase converts testosterone to DHT in the peripheral tissues that have testosterone receptors.

So it would make more sense that they are directly correlated, not inversely correlated.

 

[Primordial Performance]

If your 5a-reductase peripheral tissues grow (ie, the protstate) you can find yourself with a higher DHT/T ratio.

-Pp

 

[Tatyana]

If your 5a-reductase peripheral tissues grow (ie, the protstate) you can find yourself with a higher dihydrotestosterone/T ratio.

-Pp

Interesting. This however would indicate that there is some pathology with the prostate gland I would think...........................

 

[Mavafanculo]

If your 5a-reductase peripheral tissues grow (ie, the protstate) you can find yourself with a higher dihydrotestosterone/T ratio.

-Pp

depending on which school of thought you subsribe to (estrogen or dht being prostate unfriendly), this might be a chicken or the egg question.

iow is your BPH (enlarged prostate) caused by higher d.h.t./test ratio, or is the the higher d.h.t./test ratio caused by the enlarged prostate and associated higher 5ar

 

[eddymerckx]

so why do you go bald as you age? should you not start out bald and grow more hair as test decrease? if so, i demand my hair back

 

[Primordial Performance]

depending on which school of thought you subsribe to (estrogen or dihydrotestosterone being prostate unfriendly), this might be a chicken or the egg question.

iow is your BPH (enlarged prostate) caused by higher d.h.t./test ratio, or is the the higher d.h.t./test ratio caused by the enlarged prostate and associated higher 5ar

I was giving an example of an enlarged prostate caused by outside sources which leads to more 5a-reductase activity, thus higher DHT levels.

Outside sources being various estrogen metabolites, inflammatory responses, IGF-1, prostaglandins, leuc’s, ect.

-Pp

 

[st8grad]

That has more to do with guys that have hair follicles that are susceptible to DHT rather than how much DHT you produce. Although the amount of course is a factor.

so why do you go bald as you age? should you not start out bald and grow more hair as test decrease? if so, i demand my hair back

 

[b_light]

I think there is more to the hairloss eddy, the way i look at it is that DHT can speed up the process of hairloss if you are already prone to it so w/o anabolix its just gonna run its natural course.

 

[lanky]

overall what i have been reading over the past 6 or so years is that the prostate does not have any significant contribution to blood DHT levels...i will try to stir up some evidence.

 

[Primordial Performance]

overall what i have been reading over the past 6 or so years is that the prostate does not have any significant contribution to blood dihydrotestosterone levels...i will try to stir up some evidence.

When prostate's are removed men’s 5a-reduced metabolites plummet, sex drive goes away and men become suicidal. It’s bad.

-Pp

 

[eddymerckx]

I think there is more to the hairloss eddy, the way i look at it is that dihydrotestosterone can speed up the process of hairloss if you are already prone to it so w/o anabolix its just gonna run its natural course.

i took dura for a year when not on gear and i regrew a lot of hair and the rest got thicker---but it is an evil drug--made me feel like i was 60--sex drive/strength/attitude.

i went on a cycle just to feel like a man again and would only rub dura again if i was on a test cycle

 

[SuperOne]

I also used Dutasteride and it made me feel like i was 60 aswell for the most part, some days were better than others, but it worked great for my hair. I dont think it was directly related to low DHT totally, but other hormonal cascades going on like thyroid, estrogen,test,adrenal,ect.


Once i see my Endo and get my current situation dealt with, i think im going to try Dutasteride again with 100mg of Test C per week, low dose Aromasin, low dose T3, mabye low dose GH ( 1iu EOD ), and some Dermacrine/DHEA.


These are fairly low doses, but this should allow me to use Dutasteride with less/no sides, and mabye i'll even feel better then i normally would. I'll be 24 soon, and with the career ive been working towards i cant lose my hair, it sucks, but i cant just sit back let the shit happen, it would fuck up too many things for me.

 

[Mavafanculo]

When prostate's are removed men’s 5a-reduced metabolites plummet, sex drive goes away and men become suicidal. It’s bad.

-Pp

you have prostate removal confused with marraige lol

 

[Smokescreen]

Sorry to go off the subject here. Now that we are talking about DHT. Is this true or false? Any form of synthetic Testosterone (Cypionate, Sustatanon etc) gets converted into less DHT?

But natural Test (produced from the testes) gets converted more to DHT?

 

[Primordial Performance]

Sorry to go off the subject here. Now that we are talking about dihydrotestosterone. Is this true or false? Any form of synthetic Testosterone (Cypionate, Sustatanon etc) gets converted into less DHT?

But natural Test (produced from the testes) gets converted more to DHT?

This might be true for most… but topical testosterone for instance converts mostly to dihydrotestosterone because the skin is a main site for 5a-reductase activity.

-Pp