A lot of guys will tell you gyno isn't really a problem with tren. I think there is more of a chance than people think. There has to be 3 things present to cause gyno, can't remember those 3 things at the moment sry, but nolva takes one of those out of the picture. If you're worried just run 10mg nolva ED. I'll try and dig up the posts explaining tren and gyno if i get a chance. Maybe someone can elaborate a little more on the subject than myself.
As for your liver and kidneys Tren is way overated in its harshness, IMO. Drink a lot of water. If you're drinking a gallon a day now, drink 1 1/2 to 2 gallons while on tren and you'll be pissing clear. Take ALA , milk thistle, etc...for your liver if you're worried. There isn't really anyway to be positive how it affects your liver short of a blood test. Everyone is different.