majutsu
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A newly released article suggests the pump may exist after all. In a recent study, subject animals were operated on to produce a venous blockage. Since blood goes into the muscle through the arteries and leaves via the veins, blocking veins will generally lead to the engorgement of the muscle with blood.
This is very similar to the "pump". In this scenario, the bodybuilder performs many repetitions of a light weight with little rest. The effect in to cause localized swelling in the muscle, which when coupled with the mechanical effects of the repeated movement, produce a "tightness" and venous occlusion with blood engorgement. Also, when blood becomes stagnant, oxygen flow is poor, and there is a build-up of lactic acid. The tightness, blood engorgement and burning sensation is colloquially called the "pump".
Many modern pseudo-scientists, professing knowledge not yet certain in fact, have been fond of brow-beating experienced bodybuilders who value the pump based on their experience. "The pump has nothing to do with building muscle," they scream.
In a recent study, a pump was produced surgically by venous occlusion. The pump group showed significantly more weight gain in the muscle. Furthermore, it was protein, real muscle, not just water weight as some have alleged. Interestingly, the mechanism seems to have nothing to do with IGF. The authors suspect myostatin as the causative agent.
The abstract and reference is attached below:
Med Sci Sports Exerc. 2005 Jul;37(7):1144-50. Related Articles, Links
Skeletal muscle hypertrophy after chronic restriction of venous blood flow in rats.
Kawada S, Ishii N.
Institute of Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa-shi, Chiba Prefecture, Japan. [email protected]
PURPOSE: Some previous studies have shown that resistance exercise training with venous occlusion causes an enhanced hypertrophy in human muscles. To investigate the effects of blood flow on muscular size at either cellular or subcellular level, we developed an animal model in which several veins from hindlimb muscles of the rat are surgically crush-occluded. METHODS: Twenty-four male Wister rats were randomly assigned into either a group for sham operation (sham group) or a group for venous occlusion (experimental group; N = 12 for each group). Fourteen days after the operation, plantaris, soleus, gastrocnemius, extensor digitorum longus, and tibialis anterior muscles were dissected from hindlimbs and subjected to morphological and biochemical analyses. RESULTS: Fourteen days after the operation, the muscles expect for soleus showed similar increases in wet weight/body weight (by 7-12%) as compared with the sham-operated group (P < 0.05). Further analyses on the plantaris muscle showed increases in muscle dry weight/ body weight (by 10%) and the concentrations of myofibrillar protein (by 23%), glycogen (by 93%) and lactate (by 23%) after the operation (P < 0.05). Mean fiber cross-sectional area was larger by 34% in the experimental group than in the sham-operated group (P < 0.01). The content of HSP-72 increased, whereas that of myostatin protein decreased (P < 0.01). The expression of nitric oxide synthase-1 (NOS-1) mRNA increased (P < 0.01), whereas that of IGF-1 mRNA showed no significant change (P = 0.36). Although the muscle nitric oxide (NO) concentration tended to increase, but the change was not significant (P = 0.10). CONCLUSIONS: Changes in muscle blood flow may affect the muscular size through actions of HSP-72, myostatin, and NOS-1.
This is very similar to the "pump". In this scenario, the bodybuilder performs many repetitions of a light weight with little rest. The effect in to cause localized swelling in the muscle, which when coupled with the mechanical effects of the repeated movement, produce a "tightness" and venous occlusion with blood engorgement. Also, when blood becomes stagnant, oxygen flow is poor, and there is a build-up of lactic acid. The tightness, blood engorgement and burning sensation is colloquially called the "pump".
Many modern pseudo-scientists, professing knowledge not yet certain in fact, have been fond of brow-beating experienced bodybuilders who value the pump based on their experience. "The pump has nothing to do with building muscle," they scream.
In a recent study, a pump was produced surgically by venous occlusion. The pump group showed significantly more weight gain in the muscle. Furthermore, it was protein, real muscle, not just water weight as some have alleged. Interestingly, the mechanism seems to have nothing to do with IGF. The authors suspect myostatin as the causative agent.
The abstract and reference is attached below:
Med Sci Sports Exerc. 2005 Jul;37(7):1144-50. Related Articles, Links
Skeletal muscle hypertrophy after chronic restriction of venous blood flow in rats.
Kawada S, Ishii N.
Institute of Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa-shi, Chiba Prefecture, Japan. [email protected]
PURPOSE: Some previous studies have shown that resistance exercise training with venous occlusion causes an enhanced hypertrophy in human muscles. To investigate the effects of blood flow on muscular size at either cellular or subcellular level, we developed an animal model in which several veins from hindlimb muscles of the rat are surgically crush-occluded. METHODS: Twenty-four male Wister rats were randomly assigned into either a group for sham operation (sham group) or a group for venous occlusion (experimental group; N = 12 for each group). Fourteen days after the operation, plantaris, soleus, gastrocnemius, extensor digitorum longus, and tibialis anterior muscles were dissected from hindlimbs and subjected to morphological and biochemical analyses. RESULTS: Fourteen days after the operation, the muscles expect for soleus showed similar increases in wet weight/body weight (by 7-12%) as compared with the sham-operated group (P < 0.05). Further analyses on the plantaris muscle showed increases in muscle dry weight/ body weight (by 10%) and the concentrations of myofibrillar protein (by 23%), glycogen (by 93%) and lactate (by 23%) after the operation (P < 0.05). Mean fiber cross-sectional area was larger by 34% in the experimental group than in the sham-operated group (P < 0.01). The content of HSP-72 increased, whereas that of myostatin protein decreased (P < 0.01). The expression of nitric oxide synthase-1 (NOS-1) mRNA increased (P < 0.01), whereas that of IGF-1 mRNA showed no significant change (P = 0.36). Although the muscle nitric oxide (NO) concentration tended to increase, but the change was not significant (P = 0.10). CONCLUSIONS: Changes in muscle blood flow may affect the muscular size through actions of HSP-72, myostatin, and NOS-1.

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