Testosterone suppreses the immune system?

[big_boy_1]

immunomodulators, altering the sensitivity of the immune system. For example, female sex hormones are known immunostimulators of both adaptive[86] and innate immune responses.[87] Some autoimmune diseases such as lupus erythematosus strike women preferentially, and their onset often coincides with puberty. By contrast, male sex hormones such as testosterone seem to be immunosuppressive.[88]
Immune system - Wikipedia, the free encyclopedia

The suppressive effects of male sex hormones on immune functions have been observed in a wide variety of disease processes and appear to be testosterone-mediated. Endogenous testosterone inhibits skin wound healing response in males and is associated with an enhanced inflammatory response.
Influence of physiological androgen levels on wound healing and immune status in men - The Aging Male

What you can do to minimize this supression?

 

[galaxy]

Not in my opinion. I rarely get sick and know a 60yr old who juiced for 20yrs whos never missed a day of work.

 

[drsketch]

They also give steroids to HIV and full blown aids patients with auto immune diseases..

 

[galaxy]

The immune system may be depressed post cycle when your crashing if anything.

 

[lartinos]

coming off tren or deca is the only thing that ever weakened mine in my opinion.

 

[needtogetaas]

They also give steroids to HIV and full blown aids patients with auto immune diseases..

True.

I do feel it has some truth to it though.

 

[drsketch]

I think it mildly suppresses it, nothing a good diet with vitamins(especially vitc) and minerals cant combat though...

 

[needtogetaas]

I think it mildly suppresses it, nothing a good diet with vitamins(especially vitc) and minerals cant combat though...

Yup

 

[bw1]

Not in my opinion. I rarely get sick and know a 60yr old who juiced for 20yrs whos never missed a day of work.

Exactly...I am sick of the negative bullshit reports put out there. I believe there are many benefits with test supplementation if done properly:


Is testosterone supplementation for the aging man a good idea?

More recently, many heart disease experts have been intrigued by studies showing that men with lower testosterone levels have higher rates of heart disease. In early December 2007, for example, researchers from the United Kingdom published a study showing that men with low testosterone levels were more likely to die from cardiovascular disease and from cancers. The men with the highest levels of testosterone had a 30% lower risk of dying compared to the men with lowest levels.

And this isn't the first study to show that lower testosterone levels are associated with higher death rates, particularly from heart disease. Other types of research suggest that beneficial effects from testosterone upon the heart are quite plausible. For example:

Testosterone can dilate arteries, leading to lower blood pressure.
Higher testosterone levels are associated with a lower amount of calcium deposits in the walls of arteries (a finding that suggests lower rates of atherosclerosis).
Lower testosterone levels are associated with a higher rate of diabetes, an important risk factor for heart disease.
Higher testosterone levels are associated with lower total cholesterol and lower low density lipoprotein ("bad") cholesterol levels, and higher high density lipoprotein ("good") cholesterol - all changes associated with a lower risk of heart disease.
With this much evidence suggesting that testosterone might be beneficial, and plenty of data showing that it can make men in particular feel better, why not take it now?

 

[FunFun]

Lower testosterone levels are associated with a higher rate of diabetes, an important risk factor for heart disease.

I'm pre-diabetic. My natural testosterone production is low.

Just before a started a course of testosterone (sustanon 250/ 350 mg per week) in April my HbA1c was 5.7 (that's an average of blood glucose over a 3 month period). That corresponds to a average blood glucose of 126mg/Dl.

After 2 months on testosterone my HbA1c went down to 4.9. That corresponds to an average blood glucose of 97 mg/Dl.

My FBS (fasting blood sugar) readings were always over 100 and averaging around 110. After 2 months on testosterone they were always under 100.

My training before I started the course of testosterone was intense and my diet was good. Nothing has changed except the addition of exogenous testosterone.

I must mention here that previous to my recent course of testosterone I was training naturally for 3 years. I must also mention that I don't limit carbohydrates in my diet and consume as much as would be expected of any serious bodybuilder.

These numbers may not mean much for anyone who doesn't have diabetes, but for anyone with knowledge of such things, these results are astounding.

Exogenous testosterone has completely normalized my blood sugar readings. If a doctor tested me now he would consider me completely normal.

 

[bw1]

I'm pre-diabetic. My natural testosterone production is low.

Just before a started a course of testosterone (sustanon 250/ 350 mg per week) in April my HbA1c was 5.7 (that's an average of blood glucose over a 3 month period). That corresponds to a average blood glucose of 126mg/Dl.

After 2 months on testosterone my HbA1c went down to 4.9. That corresponds to an average blood glucose of 97 mg/Dl.

My FBS (fasting blood sugar) readings were always over 100 and averaging around 110. After 2 months on testosterone they were always under 100.

My training before I started the course of testosterone was intense and my diet was good. Nothing has changed except the addition of exogenous testosterone.

I must mention here that previous to my recent course of testosterone I was training naturally for 3 years. I must also mention that I don't limit carbohydrates in my diet and consume as much as would be expected of any serious bodybuilder.

These numbers may not mean much for anyone who doesn't have diabetes, but for anyone with knowledge of such things, these results are astounding.

Exogenous testosterone has completely normalized my blood sugar readings. If a doctor tested me now he would consider me completely normal.

Good stuff

 

[OMEGA]

~In higher doses Yes is can

~It also inhibits college/ connective tissue in high doses ( yes its documented 99% sure just dont have it)

~In HRT or normal cycle doses its obviously great though!

 

[FunFun]

~In higher doses Yes is can

What do you consider higher doses?

 

[bw1]

What do you consider higher doses?

That's a broad question. What may be high for some is not high for others.

 

[OMEGA]

That's a broad question. What may be high for some is not high for others.

titcr

 

[FunFun]

titcr

I have no idea what "titcr" means, but I suspect it's nothing nice.

You made a comment that test in higher doses can suppress the immune system. How about a broad idea of what would be considered high for a 200 lb bodybuilder in good health.

eg. 500 to 1000 mg, 1000 - 1500 mg etc.

 

[Big_Joe]

immunomodulators, altering the sensitivity of the immune system. For example, female sex hormones are known immunostimulators of both adaptive[86] and innate immune responses.[87] Some autoimmune diseases such as lupus erythematosus strike women preferentially, and their onset often coincides with puberty. By contrast, male sex hormones such as testosterone seem to be immunosuppressive.[88]
Immune system - Wikipedia, the free encyclopedia

The suppressive effects of male sex hormones on immune functions have been observed in a wide variety of disease processes and appear to be testosterone-mediated. Endogenous testosterone inhibits skin wound healing response in males and is associated with an enhanced inflammatory response.
Influence of physiological androgen levels on wound healing and immune status in men - The Aging Male

What you can do to minimize this supression?

Testosterone does not suppress the immune system. It has been know for a very long time that testosterone actually enhances the immune system. Especially the bodies ability to defend it's self from viral attack. I think you might consider doing more research on the topic if you want to learn about this wondrous machine we call our bodies.

 

[bsdgeek]

Exactly...I am sick of the negative bullshit reports put out there. I believe there are many benefits with test supplementation if done properly:


Is testosterone supplementation for the aging man a good idea?

More recently, many heart disease experts have been intrigued by studies showing that men with lower testosterone levels have higher rates of heart disease. In early December 2007, for example, researchers from the United Kingdom published a study showing that men with low testosterone levels were more likely to die from cardiovascular disease and from cancers. The men with the highest levels of testosterone had a 30% lower risk of dying compared to the men with lowest levels.

And this isn't the first study to show that lower testosterone levels are associated with higher death rates, particularly from heart disease. Other types of research suggest that beneficial effects from testosterone upon the heart are quite plausible. For example:

Testosterone can dilate arteries, leading to lower blood pressure.
Higher testosterone levels are associated with a lower amount of calcium deposits in the walls of arteries (a finding that suggests lower rates of atherosclerosis).
Lower testosterone levels are associated with a higher rate of diabetes, an important risk factor for heart disease.
Higher testosterone levels are associated with lower total cholesterol and lower low density lipoprotein ("bad") cholesterol levels, and higher high density lipoprotein ("good") cholesterol - all changes associated with a lower risk of heart disease.
With this much evidence suggesting that testosterone might be beneficial, and plenty of data showing that it can make men in particular feel better, why not take it now?

RIGHT ON! RIGHT ON MY BROTHA!! i'm so sick and tired of so-called studies pointing to male hormone as bad, if the fuckin truth was known, those studies were probably conducted by some feminist dyke nazi. like another guru on this website who put it in an ebook said- "why is it ok for a man to take female hormones to become a woman, but it's a crime for him to take male hormones to become more manly?" - this may not be word for word from his book, but it sums it up.

do i think test will suppress the immune system? no, if it did, we'd all be sick as hell everyday during puberty. do i think some of the esters, as well as whatever good test gets cut with (grapeseed oil, etc) from bunk UGL's may have an effect on the immune system? maybe. there could be any number of reasons for getting sick, i don't think test plays as much of a roll as it's blamed for sometimes.

 

[Invicta1]

They also give steroids to HIV and full blown aids patients with auto immune diseases..

True, but for autoimmune disorders they give catabolic steroids like prednisone, methylprednisolone, etc. rather than anabolic.

 

[drsketch]

True, but for autoimmune disorders they give catabolic steroids like prednisone, methylprednisolone, etc. rather than anabolic.

you 100% sure of this, I thought they gave AAS to Aids patients.

 

[bsdgeek]

True, but for autoimmune disorders they give catabolic steroids like prednisone, methylprednisolone, etc. rather than anabolic.

No, sorry bro, not buying it. The more muscle mass, lean mass you have, the better at fighting off disease. This is a medical fact, prednisone and other 'catabolic'(corticosteroids) steroids are pretty much anti-inflammatory steroids for helping reduce swelling etc etc when someone has asthma or trauma to a joint, or muscle injury where the body is over reacting and inducing inflammation. These help to rid fluid build up, and too much of some of these can dehydrate you. This wouldn't be good for someone with advanced hiv or aids, however, anavar would be. Just google search prednisone, you'll get a better understanding of it's primary uses. Here's a link:

MedlinePlus Drug Information: Prednisone

It does state that it's(prednisone) used in conjunction with antibiotics for people with aids who have pneumonia. Again, pneumonia is basically fluid buildup on the lungs.

Here's one that the end results prove that the testosterone control group actually had a decrease in viral load:

Effects of Testosterone and Progressive Resistance Training in Eugonadal Men with AIDS Wasting: A Randomized, Controlled Trial -- Grinspoon et al. 133 (5): 348 -- Annals of Internal Medicine

and here's one about how hgh actually helps aids patients:

Hormone Helps AIDS Patients Gain Weight - New York Times

I think you were partially correct, but you were also partially wrong. Corticosteriods are good for what they are used for, fighting infection, and disease, that's already there. They do not however, improve quality of life, as AAS can, as a matter of fact, after being on a cortico for a while, you'll actually start to feel like shit, I know I have when I've had to take them. my 2.

 

[big_boy_1]

Now it turns out there are at least 2 types of immune system and yes, you can have too much or too little of each other, even both at the same time.

As some said test causes flu (some reduced immunity against colds) yet estrogen worsens some (if not most) autoimmune diseases.
Progesterone and Deca promotes other immune system and reduces inflammation.