bosshogg30
New member
I found this interesting..... Wonder if tatoo guns would make any improvements as a better gear delivery system?
http://health.yahoo.com/experts/hea...hod-shows-promise-as-vaccine-delivery-system/
I've never understood the fascination with tattoos and even get annoyed when I see them. However, we may have a new, valuable use for them, or at least for the tool that creates them.
Exciting studies now suggest that injecting DNA-containing vaccines with a tattoo gun (lacking the ink that normally creates the tattoo) is far more effective than the way human vaccines are now delivered.
A German study published this month in Genetic Vaccines and Therapy showed that administering pieces of DNA from the human papillomavirus virus into the skin of mice by three tattoo-gun injections produced a 200-fold greater production of antibodies to the virus than was achieved with the old method of a needle injection into a muscle.
Vaccines made with bits of DNA are not new, but the usual ways of delivering them have not worked very well. The reason that tattoo injections are so much more effective is thought to be because the repeated puncturing of the skin by the rotating tattoo needle does real damage to the skin — the presence of a bona fide wound causes inflammatory cells to flood into the site, where they speed and enhance the immune response to the vaccine.
This skin damage, however, is also painful, and this fact may limit the application of the tattoo-injection technique for routine vaccinations. But the new technique shows promise for the use of DNA injections to treat, rather than prevent, diseases like cancer or possibly even HIV infection, where potential benefits would outweigh the pain of the injections.
Still, the technique could also prove useful for some of the more common preventive vaccinations. The reason for this is that the standard procedure for preparing vaccines is presently often time-consuming because inactivated forms of a virus must be grown inside chicken eggs. DNA vaccines, on the other hand, can be grown in bacteria, an approach that makes it possible to produce DNA vaccines in large quantities and much faster than current procedures.
The use of tattoo injections, coupled with the ability to rapidly produce large quantities of a vaccine, might prove extraordinarily valuable in a situation such as a threatened terrorist attack, where a sudden need arises for large amounts of an effective vaccine.
http://health.yahoo.com/experts/hea...hod-shows-promise-as-vaccine-delivery-system/
I've never understood the fascination with tattoos and even get annoyed when I see them. However, we may have a new, valuable use for them, or at least for the tool that creates them.
Exciting studies now suggest that injecting DNA-containing vaccines with a tattoo gun (lacking the ink that normally creates the tattoo) is far more effective than the way human vaccines are now delivered.
A German study published this month in Genetic Vaccines and Therapy showed that administering pieces of DNA from the human papillomavirus virus into the skin of mice by three tattoo-gun injections produced a 200-fold greater production of antibodies to the virus than was achieved with the old method of a needle injection into a muscle.
Vaccines made with bits of DNA are not new, but the usual ways of delivering them have not worked very well. The reason that tattoo injections are so much more effective is thought to be because the repeated puncturing of the skin by the rotating tattoo needle does real damage to the skin — the presence of a bona fide wound causes inflammatory cells to flood into the site, where they speed and enhance the immune response to the vaccine.
This skin damage, however, is also painful, and this fact may limit the application of the tattoo-injection technique for routine vaccinations. But the new technique shows promise for the use of DNA injections to treat, rather than prevent, diseases like cancer or possibly even HIV infection, where potential benefits would outweigh the pain of the injections.
Still, the technique could also prove useful for some of the more common preventive vaccinations. The reason for this is that the standard procedure for preparing vaccines is presently often time-consuming because inactivated forms of a virus must be grown inside chicken eggs. DNA vaccines, on the other hand, can be grown in bacteria, an approach that makes it possible to produce DNA vaccines in large quantities and much faster than current procedures.
The use of tattoo injections, coupled with the ability to rapidly produce large quantities of a vaccine, might prove extraordinarily valuable in a situation such as a threatened terrorist attack, where a sudden need arises for large amounts of an effective vaccine.