I have done two 6w cycles of T3.
Started out at 25 mcg and peaking for 10 days at 150 mcg, then down to 12,5 in the end of the cycle.
I did notice some sides.
My blood glucose levels were sooo low most of the times, couldn't eat enough to keep it up. Low blood sugar = instant depression.
But for me, it was definitely worth it.
For my next T3 cycles, I don't think I'll go over 100 mcg / day.