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T3 vs. T4

I would prefer t4 just because it's "safer". By that I mean you dont need to taper up and down like T3 and can stay on longer. Also, mis-dosings with T4 aren't as dangerous as T3.
 
52_21_30 said:
I would prefer t4 just because it's "safer". By that I mean you dont need to taper up and down like T3 and can stay on longer. Also, mis-dosings with T4 aren't as dangerous as T3.

There is NO, I repeat NO danger to exogenous T3 usage. It has no permanent affects on the human thyroid, and cardiovascular problems generally only arise if your cardiovascular state has already been compromised vis-a-vis a medical condition. I hate to break it, but this is just an old wives tale. Also, It is wise to taper up and down any drug, be it T4, T3, clen or any of these.


An early study that looked at thyroid function and recovery under the influence of exogenous thyroid hormone was undertaken by Greer (2). He looked at patients who were misdiagnosed as being hypothyroid and put on thyroid hormone replacement for as long as 30 years. When the medication was withdrawn, their thyroids quickly returned to normal.




"In 1951, Greer reported the pattern of recovery of thyroid function after stopping suppressive treatment with thyroid hormone in euthyroid [normal] subjects based on sequential measurements of their thyroidal uptake of radioiodine. He observed that after withdrawal of exogenous thyroid therapy, thyroid function, in terms of radioiodine uptake, returned to normal in most subjects within two weeks. He further observed that thyroid function returned as rapidly in those subjects whose glands had been depressed by several years of thyroid medication as it did in those whose gland had been depressed for only a few days" (3)




The implications to this discovery are quite massive. In direct contradiction to the propaganda of many noted sources of bodybuilding literature, the administration of exegenous T3 will not produce any lasting negative effects on the human thyroid. This hormone can be administered indefinately without negative glandular reprocussions.



These results have been subsequently verified in several studies.(3)(4)
(2)(Greer,M. N Engl J Med 244:385, 1951)

(3)N Engl J Med 1975 Oct 2;293(14):681-4 Recovery of pituitary thyrotropic function after withdrawal of prolonged thyroid-suppression therapy. Vagenakis AG, Braverman LE, Azizi F, Portinay GI, Ingbar SH.

(4) J Clin Endocrinol Metab 1975 Jul;41(1):70-80 Patterns off recovery of the hypothalamic-pituitary-thyroid axis in patients taken of chronic thyroid therapy. Krugman LG, Hershman JM, Chopra IJ, Levine GA, Pekary E, Geffner DL, Chua Teco GN
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Whats the concensus on the usage and duration of t3 then, some say its safe to use at the correct dosage over a long period of time and some say no longer than 4-6 weeks?

Which case seems to hold true by the majority of experts?
 
Vascular Freak said:
Whats the concensus on the usage and duration of t3 then, some say its safe to use at the correct dosage over a long period of time and some say no longer than 4-6 weeks?

Which case seems to hold true by the majority of experts?

VasFreak, Please Carefully read my above posted article. This is not based on personal opinon but rather science.

This was a scientific finding in T3 study originally on patients who were misdiagnosed as being hypothyroid and put on thyroid hormone replacement for as long as 30 years. When the medication was withdrawn, their thyroids quickly returned to normal.

This was shown by multiple radioiodine scan testings administered to all patients after administration of the hormone was ceased.
. The article went on to say that the "results have been subsequently verified in several studies.(3)(4)
(2)(Greer,M. N Engl J Med 244:385, 1951)"
 
does it make any sense to take both t4 and t3 with hgh?

i am on
2iu gh ed
t4 100 mcg ed
t3 5mcg ed
prop 50 mg eod

i want to taper up the t4 to 200-300 ed because i read 25 mcg of t3 is equal to 100 mcg of t4. this is for fat loss. what do u think?
 
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