T3 Split Dose?

[dr_skier]

What is the half life of T3 in your body? Is it nessessary to split the dose am/pm? Thanks.

 

[Makavelli]

What is the half life of T3 in your body? Is it nessessary to split the dose am/pm? Thanks.

I take it all at once.

 

[Themachine01]

I take it all at once.

same here, first thing in the morning.

 

[big_boy_1]

What is the half life of T3 in your body? Is it nessessary to split the dose am/pm? Thanks.

Half life 2 1/2 days, not needed, but if you can split the dose, do it, may help somewhat.

CLINICAL PHARMACOLOGY

The mechanisms by which thyroid hormones exert their physiologic action are not well understood. These hormones enhance oxygen consumption by most tissues of the body and increase the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins. Thus, they exert a profound influence on every organ system in the body and are of particular importance in the development of the central nervous system.

Pharmacokinetics

Since liothyronine sodium (T3) is not firmly bound to serum protein, it is readily available to body tissues. The onset of activity of liothyronine sodium is rapid occurring within a few hours. Maximum pharmacologic response occurs within 2 or 3 days, providing early clinical response. The biological half-life is about 2-½ days.

T3 is almost totally absorbed, 95 percent in 4 hours. The hormones contained in the natural preparations are absorbed in a manner similar to the synthetic hormones.

Liothyronine sodium has a rapid cutoff of activity which permits quick dosage adjustment and facilitates control of the effects of overdosage, should they occur.

 

[scout69]

I used it twice once splitting between AM and PM and the second time just one daily during the AM and the results where the same to me so it's really up to you...

 

[Outtlaw]

I also take it all in the AM. Tried taking it in the PM and splitting the dose but neither had positive effects for me.

 

[d.s.]

I used it twice once splitting between AM and PM and the second time just one daily during the AM and the results where the same to me so it's really up to you...

can we see an example of how you used it ---how did you dose it, how did you start and end it.

 

[dr_skier]

So the half life is 2.5 days, active within a few hours of entering your body. Ok. but what does this mean?

Since liothyronine sodium (T3) is not firmly bound to serum protein, it is readily available to body tissues. The onset of activity of liothyronine sodium is rapid occurring within a few hours. Maximum pharmacologic response occurs within 2 or 3 days, providing early clinical response. The biological half-life is about 2-½ days.

T3 is almost totally absorbed, 95 percent in 4 hours. The hormones contained in the natural preparations are absorbed in a manner similar to the synthetic hormones.

Liothyronine sodium has a rapid cutoff of activity which permits quick dosage adjustment and facilitates control of the effects of overdosage, should they occur.


Does this mean its active but wears out quickly? so split dosing is good? Im confused.

 

[dr_skier]

bmp?

 

[big_boy_1]

So the half life is 2.5 days, active within a few hours of entering your body. Ok. but what does this mean?

That your metabloism increases (and burn fat) within a few hours, i.e. it doesnt take days or weeks to start working, like say, deca.

Liothyronine sodium has a rapid cutoff of activity which permits quick dosage adjustment and facilitates control of the effects of overdosage, should they occur.

Does this mean its active but wears out quickly? so split dosing is good? Im confused.

Its half life is 2.5 days, so in 2.5 days your blood levels drop to half.

After say a week, not much of it remains, so if you overdose and step back, in less than a week youll be back to normal.

This unlike say deca, or test cyp or worse decanoate, which remain for a couple weeks exerting their effects in your body, even after you stopped taking.

Feel free to ask if still not clear