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T-3 dosing

Dial_tone

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This has been on my mind for some time now. According to several medical sites I've come across the "The usual full replacement dose of levothyroxine sodium (T3) younger, healthy adults is approximately 1.6 mcg/kg/day administered once daily." I'm not a science guru by any stretch but I interpret this amount (perhaps incorrectly) as being the amount a healthy adult would normally produce. Is that assumption wrong? While I’m hardly young, being that I’m 250 lbs, this would put my full dosage at 181mcg/day which is way beyond what BB'ers normally take. My second question is does the thyroid really shutdown when exogenous T3 is introduced? The reason I ask is if 181mcg is what a healthy 250lb body produces then you supplement 50-75mcg/daily it seems to me you're shutting down your production but still taking less than your body would produce anyway. It seems no different front taking a 50-75mg shot of test every week...you're not really gaining anything. So where does my thinking go pear shaped? And please don't tell me what people normally take to lose weight, that is NOT what is being asked here.

side note: The vet prescribed levothyroxine for my dog recently. (no seriously). The prescription was $42 for 1,000 200mcg tabs. I didn't even look at the bottle for the first couple weeks.
 
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Here is a little excerpt from mtex @ MMSFITNESS

T-3 is a synthetic thyroid hormone that will increase the metabolism & also stimulate protein synthesis. for this reason it works well when added to a cycle. you should start with a low dosage, about 25 mcgs. per day and increase by about one tab or 25 mcgs. per day every few days. i dont recomend that you exceed 100 mcgs. per day. On days that you take multiple tabs, divide the tabs evenly across the day (i.e. 100 mcgs. would be 4 doses of 25 mcgs. apiece spread evenly across the day.) You also need to make sure that you cycle down off this product as well to keep the thyroid functioning properly as well. i recomend 5 weeks running cycles & 8 week layoff before doing it again as to allow normal thyroid functioning to return.

clen has thermogenic, fat burning as well as some anti catobolic properties. Clenbuterol acts as a CNS stimulant and users commonly report side effects such as shaky hands, insomnia, sweating, increased blood pressure and nausea. These side effects usually subside within 2-3 days as the user becomes accustomed to the drug. the fat burning effects of clen will subside in 2-4 weeks usually. you should tper the doses up to get used to it but really no need to taper down IMO. i suggest 3 weeks on 2 weeks off.


suggested doses: clen - start w/ 1 tab on the first day (20mcgs) and then increase the dosage by one tablet each day until the desired maximum dosage is reached.

T-3 : start w/ 1 tab a day (25 mcgs) , increase by one tab evey few days , not to exceed 100 mcg's a day then taper down in the last week of a 5 week cycle back to 25 mcgs a day.

you should spread the doses through the day , i dont recomend taking the entire dose of T-3 & clen all at once.

IMO this is one of the best fat burning combos available today combined w/serious training & proper diet can yeild good results. & dont even ask about DNP, we wont go there
 
Dial_tone said:
. According to several medical sites I've come across the "The usual full replacement dose of levothyroxine sodium (T3) younger, healthy adults is approximately 1.6 mcg/kg/day administered once daily." I'm not a science guru by any stretch but I interpret this amount (perhaps incorrectly) as being the amount a healthy adult would normally produce. Is that assumption wrong? While I’m hardly young, being that I’m 250 lbs, this would put my full dosage at 181mcg/day which is way beyond what BB'ers normally take.
.

i think u messed t3 with t4 bro,levothyroxine sodium is t4 thus the high dose recomended,so having in mind that t4 converts into t3 at a rate of about 4:1(im no expert here) the recomended dose for a replacement therapy with t3 should be 0,4 mcg daily,100 mcg for ya.From my experience and since ur a big guy 100 mcg wont do much good to ya, go for 150+mcg ed of T3
 
dim said:
i think u messed t3 with t4 bro,levothyroxine sodium is t4 thus the high dose recomended,so having in mind that t4 converts into t3 at a rate of about 4:1(im no expert here) the recomended dose for a replacement therapy with t3 should be 0,4 mcg daily,100 mcg for ya.From my experience and since ur a big guy 100 mcg wont do much good to ya, go for 150+mcg ed of T3

http://www.rxlist.com/cgi/generic/unithroid_ids.htm

http://www.annals.org/cgi/content/full/119/6/492

http://www.centerwatch.com/patient/drugs/dru789.html

I can find more if you want.
 
BBF has a lot of knowledge on this subject and has shared some with me. Maybe if you could ask him?
 
hm sure go ahead find more but what does it have to do with my post?
all these talk about levothyroxine sodium whitch is t4 and ur asking for a "t3-dosing"
 
It all depends on the severity of hypothyroidism, but I have rarely heard of anyone getting more than 5mcg of cytomel 2 times per day prescribed to them. Most endocrinogists that use cytomel - will prescribe both levoxyl (at varying dosages) and cytomel at 5mcg 2 times per day. It is very, very rare for anyone to get a higher dose than that. There isn't a single person on the planet getting 50-75 mcg of cytomel per day prescribed, thats just totally ridiculous....well maybe if their thyroid was removed or something, but otherwise no.

You can search google groups - but that is the concensus that i have come to. And yes, exogenous T3 will suppress TSH (at any dosage) - which in turn suppresses t4 and t3 production.
 
poantrex said:
There isn't a single person on the planet getting 50-75 mcg of cytomel per day prescribed, thats just totally ridiculous....well maybe if their thyroid was removed or something, but otherwise no.

Once again, you are wrong.

I am prescribed 50MCG twice per day, and have been for some time now.

@ DT, what dim said was right; for big guys in the 250+ range it's gonna take 150+MCG to do anything worthwhile.

Hope this helps.

DIV

:chomp:
 
DIVISION said:
Once again, you are wrong.

I am prescribed 50MCG twice per day, and have been for some time now.

@ DT, what dim said was right; for big guys in the 250+ range it's gonna take 150+MCG to do anything worthwhile.

Hope this helps.

DIV

:chomp:

Jesus christ, you must have had severe hypothyroidism. What you were prescribed is NOT COMMON. AT ALL. Typically, someone with hypothyroidism has a TSH in the 5-20 range. Supplementing with T4 (usually between 100 and 200 mcg a day) and T3 (5 mcg twice daily) is sufficient to get into the normal range. Most doctors prescribe levoxyl at 100 to 200mcg a day only without cytomel, and even that is sufficient to bring T3 and T4 to the normal range. If you don't believe me, you can read some of prescribed dosages over at google groups, and its rare for anyone to get even 25mcg per day unless they have extremely severe hypothyroidism.

http://groups.google.com/groups?hl=en&lr=&ie=UTF-8&c2coff=1&q=cytomel+dosage

What were your TSH, Free T3, and Free T4 numbers before getting this?
Cytomel is not prescribed according to bodyweight, it is prescribed to get into the normal range of thyroid hormone. It DOES NOT take a lot of T3 to get into the normal range of T3. I find it HARD TO BELIEVE that it requires ANYONE 100mcg of t3 to get into the "normal range".

And by the way, dbol sucks.
 
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Now that I think about it, i'm inclinced to call BS on this. Who is your endo, that is prescribing such a ridiculously high amount of t3? 100mcg of T3 per day is nuts because it FAR exceeds normal production. You may be right that 100-150mcg of T3 is necessary for weight loss (nevermind TSH suppression right?) but a doc will not prescribe cytomel for weight loss.
 
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Whoa whoa whoa...I just noticed this. Dialtone: levothyroxine is not T3 - it is T4. T3 would be referred to as triiodothyronine. That would explain the dosage discrepancy in your post.
 
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