some info
Diuretics are prescription drugs that increase urination and help eliminate water and sodium from the body. They reduce bloating in women with PMS and also have a beneficial effect on mood, breast tenderness, and food craving. Spironolactone (Aldactone) is most commonly used for this purpose. Other common diuretics include hydrochlorothiazide (Esidrix, HydroDiuril) and furosemide (Lasix). Unless potassium is replaced, many diuretics deplete the body's supply of potassium, possibly leading to heart rhythm disturbances. Spironolactone, however, is known as a potassium-sparing drug and does not have this problem, although women should be sure not to take additional potassium if they chose spironolactone. Diuretics should not be used for mild or moderate PMS symptoms. They should not be taken with certain antidepressants, and women taking other medications should check with their doctors about possible drug interactions.
spironolactone
Miller-Keane Medical Dictionary, 2000
(spi´´ro-no-lak´tön) a synthetic 17-spirolactone steroid that is a competitive antagonist of aldosterone, which blocks the aldosterone-dependent exchange of sodium and potassium in the distal tubule, thus increasing the excretion of sodium and water and decreasing the excretion of potassium; used in the treatment of edema due to congestive heart failure or hepatic or renal disease, in the treatment of hypokalemia, in the management of primary hyperaldosteronism, and, usually in combination with other drugs, in the treatment of hypertension.