This may sound materialistic, but the lakehouse.
My two grandfathers built it when I was a month old. All my life its been there. So many memories of boats, fishing, motorcycles, Fourth of July, exploring the woods, and yes, even all the repairs.
It was there when my wife and I seperated and I had a place to live. It was there when we were dating and needed a place "to go". Three generations of kids have enjoyed it.
Its sanctuary.
I have a nice house in the burbs, but I'll take that little lakehouse anyday....