Straker said:
Puertorico (or anyone else for that matter) - How much would I need of these compounds for them to be of use? And for how long did you take them?
thanks
Here's some great info I found.Although just to clear matters up, the pantothenic acid/choline combo works on strengthening the cholinergic system,particularly the neurotransmitter acetylcholine.
Acetyl-L-Carnitine would also work excellent for this purpose as it has also demonstrated phenomenol acetylcholine enhancing efffects.
If one also wishes to strenghthen dopaminergic integrity, then these DA's can be added for good results...L-Tyrosine,selegeline hcl(eldepryl),hydergine,amantadine, and dostinex.
Choline and Vitamin B5
Sexual arousal occurs not just in the genitals but in the whole body and, especially, in the brain. For men, it actually begins when the brain sends impulses down the spinal cord and out to the nerves that serve the penis. These impulses trigger the production of nitric oxide (NO), which causes penile arteries to dilate and the spongy core of the penis to relax and become engorged with blood. The neurotransmitter that carries the sexual message is acetylcholine (ACh). ACh also seems to control sexual behavior through its activity in the brain. For women, ACh is also a very important part of sexual function.
Numerous studies confirm a key role for cholinergic nerve transmission in sexual responses. Simply speaking, with too little ACh, sexual activity goes down. Increase ACh levels, and sexual activity goes up. ACh is involved in the build-up toward orgasm and the urethral and vaginal contractions that occur during orgasm as well as the subjective perception of orgasm intensity and duration.
In addition to its direct role in the sexual response, ACh is also the primary chemical the body uses to transmit signals from nerves to skeletal muscles, the muscles that move the body. You need this chemical for muscular control and proper muscle tone. There is reason to believe that enhancing cholinergic neuromuscular transmission will enhance your energy and stamina by raising your ACh levels and that this can provide indirect sexual benefits by allowing you to perform longer and with more energy.
While drugs can enhance the body’s cholinergic activity, these drugs not only have unpleasant or even dangerous side effects, but are available only by prescription. One way to safely and effectively enhance ACh levels is to take supplements of choline, along with vitamin B5, so that the body will manufacture more ACh.
Vitamin B5, also known as pantothenic acid or calcium pantothenate, actually seems to enhance endurance by two routes. The first is its already-mentioned role in creating ACh from choline. Second, is its role in the energy-producing Krebs Cycle, which is vital for all living cells. An early indication that vitamin B5 might increase physical endurance came from a study in which rats were placed into a tank filled with cool (64°F) water and forced to swim until they became exhausted. Prior to their swim, the rats’ diets had included either high, adequate, or deficient levels of vitamin B5. The high dose rats lasted more than four times as long as those whose diet had been B5 deficient. In another experiment, pieces of frog muscle were stimulated electrically to make them twitch. The stimulation continued until the muscle became exhausted. Muscle tissue that was bathed in vitamin B5 had double the work output as the control muscle. [Ralli, 1953].
What are the sexual effects of choline and vitamin B5?
As these results suggest, the primary sexual effect of treatment with choline and vitamin B5 or B5 alone is reported to be increased endurance. “I can generally have sex for about twice as long as I can without it,” said a man in his 30s, who takes vitamin B5 by itself.
One woman, who uses choline plus vitamin B5, says they help her feel more relaxed during sex. “There’s no muscle tightness,” she said. “It makes your body feel smoother, especially if you tend to tense up while having an orgasm.”
Dosage and timing
Experienced users recommend taking choline plus vitamin B5 or B5 by itself about 20 to 30 minutes before sex in order to get the full effect right from the start. But, notes one user, “Don’t worry if you start too soon, it’ll kick in as you’re going.” He adds that, “Not everybody will notice it, but if you set a clock, you’ll notice that you have the energy to go longer. Pretty much everyone I’ve told about B5 has had that effect.”
Combinations that many people have found effective include three times as much choline as B5 (for example, 500 - 1,000 mg of B5 in combination with 1,500 - 3,000 mg of choline). It is probably wise to begin with lower doses in this same ratio, and gradually increase the dose as tolerated.
http://www.vrp.com/art/552.asp
B32
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(6). The man’s impulse to wear women’s clothing ceased when the drug was discontinued!!
