Site injections - worth it??

[Zyglamail]

There seems to be abattle raging as to weather or not site injecting really works. There also seems to be a lot of speculation and anecdotal reports for and against. There is a quote from an abstract of a test done on the subject. Link to complete article is at the bottom.

Pharmacokinetics and Pharmacodynamics of Nandrolone Esters in Oil Vehicle: Effects of Ester, Injection Site and Injection Volume1 Charles F. Minto, Christopher Howe, Susan Wishart, Ann J. Conway and David J. Handelsman Department of Anaesthesia and Pain Management, Royal North Shore Hospital (C.F.M.), and Andrology Unit, Royal Prince Alfred Hospital, Department of Medicine (C.H., S.W., A.J.C., D.J.H.), University of Sydney, Sydney, Australia

Abstract
Top
Abstract
Introduction
Materials & Methods
Results
Discussion
References
We studied healthy men who underwent blood sampling for plasma nandrolone, testosterone and inhibin measurements before and for 32 days after a single i.m. injection of 100 mg of nandrolone ester in arachis oil. Twenty-three men were randomized into groups receiving nandrolone phenylpropionate (group 1, n = 7) or nandrolone decanoate (group 2, n = 6) injected into the gluteal muscle in 4 ml of arachis oil vehicle or nandrolone decanoate in 1 ml of arachis oil vehicle injected into either the gluteal (group 3, n = 5) or deltoid (group 4, n = 5) muscles. Plasma nandrolone, testosterone and inhibin concentrations were analyzed by a mixed-effects indirect response model. Plasma nandrolone concentrations were influenced (P < .001) by different esters and injection sites, with higher and earlier peaks with the phenylpropionate ester, compared with the decanoate ester. After nandrolone decanoate injection, the highest bioavailability and peak nandrolone levels were observed with the 1-ml gluteal injection. Plasma testosterone concentrations were also influenced (P < .001) by the ester and injection site, with the most rapid, but briefest, suppression being due to the phenylpropionate ester, whereas the most sustained suppression was achieved with the 1-ml gluteal injection. Plasma inhibin concentrations were also significantly influenced by injection volume and site, with the lowest nadir occurring after the nandrolone decanoate 1-ml gluteal injection. Thus, the bioavailability and physiological effects of a nandrolone ester in an oil vehicle are greatest when the ester is injected in a small (1 ml vs. 4 ml) volume and into the gluteal vs. deltoid muscle. We conclude that the side-chain ester and the injection site and volume influence the pharmacokinetics and pharmacodynamics of nandrolone esters in an oil vehicle in men.

Link to full article
HERE

 

[ripped1979]

yea would deca injected in the bicep do anything?

i heard it can increase the size of muscle bewcause deca is an oil base steroid...

 

[foreverblast2]

SAY WHAT?!?!?!??!

 

[JohnyJuice]

if i am not mistaken, site injections dont actually stimulate growth anymore at the site than if you had shot it in your ass or where ever. Site growth is more a product of either slight swelling or the fact that there is now a cc or so of oil taking up space in the muscle, causing an increase in size. If site injections caused actual growth, people would be walking around with disproportionate tank asses.

 

[jrodssb]

~johny
not flaming...
though funny thing is that BB have "big" asses. at least very noticeable...
also, what makes you think that everyone always shoot up in their glutes??? .

If site injections caused actual growth, people would be walking around with disproportionate tank asses.

the fact that there is now a cc or so of oil taking up space in the muscle

if that was the case I would just have a ball on the outer head of my tricep. which I don't. that would happen if the oil didn't dissipate. the oil does not take the form of a well defined muscle. you should try it!! I'm not being sarcastic.

...people on this board and anywhere else for that matter are always getting proof of scientific studies to back their arguments. I'm not knocking that at all. however, other studies like the effects of red meat, soy and even ecstacy etc.. that really matter to our society as a whole are always changing and new shit always comes out. new evidence and what not. I have to tell you. I'm a skeptic. I go by experience and by good faith. if somebody on this board brings up something that makes sense to me, I try it.
I'm ramblinig already. I'm not expert but, I tell you site injections are working great for me!!
good luck!

 

[JohnyJuice]

Hey J, i believe you. I personally dont have any experience to speak from (i havent juiced). I was speaking from what i have seen from friends and the knowledge of the vets on this board. Any other experiences?

 

[littlearnold1069]

i think site injections work..couple of weeks ago, i started injecting 1/2cc of EQ and 1/2cc of Fina into both of my medial delts...even though i haven't taken any measurements i feel as if they are bigger and fuller already...just my opinion though

 

[E-Rawk]

dude your body still has to process the drugs and turn them into hormones that make you grow. Site injecting will not make you grow. Its not like the oil tranforms into muscle wherever it is injected. It still needs to be processed. I do site injecting but only because i like to spread out the soreness. Your shoulders looked bigger cause they were full of muscle and somtimes they get swolen from being sore.

 

[Scotsman]

volume increase

Some anabolics that are site injected cause actual localized growth. Substances like pgf2a and igf1 can cause nuclear generation in muscle cells which is the mechanism for muscular growth. Oil based substances like synthol cause intramuscular volume to incrase by filling in interfiber spaces inside the muscle sheath. Some injection cause water retention which is a normal sympthetic reaction to a foreign substance being put in the body. This should decrease within a few hours or depending on the person a couple of days. The psychological effect of focusing on a muscle more because you just rammed a hollow metal tube into the area may help your spot training though.

 

[the truth]

The abstract quoted above says nothing about site-injection induced localized growth, but rather concerns itself mostly with serum levels of the hormone injected and lowering of plasma testosterone levels. I'm unsure why this study was cited--it's absolutely irrelevant to the thread topic.

BTW, site injections of AAS can and do cause localized growth, and it's not just inflammation, either. And no, I don't have any relevant studies to cite, just my own experience and that of other people who site inject (therealj comes to mind).