A recently published article from the British Journal Of Nutrition (http://www.ingenta.com/isis/searchi...&index=1&WebLogicSession=PKuH8WeFnwMUTF8GDykk|-1816452410122585988/-1052814329/6/7051/7051/7052/7052/7051/-1)
concludes that "Taken together these results suggest that high-dose supplements might not be the most efficient way of increasing the body pool of vitamin C."
It seems that, like most other systems in our body, we respond to chronic high doses of vitamin C by reducing the number of intestinal transporters required to absorb the vitamin. I have no doubt that many other vitamins and minerals are susceptible to downregulation or changes in efficiency of absorption, utilization and excretion when taken chronically. Seems to me that our bodies are designed to be most efficient when all nutrients and hormones are 'cycled'.
Note that this research was done in vitro rather than looking at whole live humans, so may not be valid in the real world. But it makes ya wonder.....................
concludes that "Taken together these results suggest that high-dose supplements might not be the most efficient way of increasing the body pool of vitamin C."
It seems that, like most other systems in our body, we respond to chronic high doses of vitamin C by reducing the number of intestinal transporters required to absorb the vitamin. I have no doubt that many other vitamins and minerals are susceptible to downregulation or changes in efficiency of absorption, utilization and excretion when taken chronically. Seems to me that our bodies are designed to be most efficient when all nutrients and hormones are 'cycled'.
Note that this research was done in vitro rather than looking at whole live humans, so may not be valid in the real world. But it makes ya wonder.....................