SERMs effects on prostate?

[MTS]

What are SERMs effects on the prostate?

 

[galaxy]

Im thinking they may be beneficial. I believe deca is also beneficial to prostate.

 

[CO B-man]

Saw Palmetto helps to promote a healthy prostate too

 

[galaxy]

As we age are less test produced causes higher levels of estrogen, so yes they are beneficial.

However that is my opinion from my research as there is no valid research done to prove why there is a 2nd growth phase with our prostate that begins around age 25.

 

[pitbullrocco]

Saw Palmetto helps to promote a healthy prostate too

every since i started popping 5-6 grams/day of SP, i don't have that uncomfortable stinging, tight feeling above my right nut, like its shrunk down a bit.

however, medical research is conflicting on this.

 

[Anthony Roberts]

Clinical data indicates SERMS are beneficial to the prostate. Some of the second generation SERMS are indicated in treatment of certain prostate issues.

 

[MTS]

Clinical data indicates SERMS are beneficial to the prostate. Some of the second generation SERMS are indicated in treatment of certain prostate issues.

that's what i wanted to know thanks.

 

[needtogetaas]

Clinical data indicates SERMS are beneficial to the prostate. Some of the second generation SERMS are indicated in treatment of certain prostate issues.

good info

 

[galaxy]

good info

What cus my name isnt Tony, my info wasnt good enuff? I mean I made a quality post, why cant i get some love?

 

[Mac173]

every since i started popping 5-6 grams/day of SP, i don't have that uncomfortable stinging, tight feeling above my right nut, like its shrunk down a bit.

however, medical research is conflicting on this.

That's alot of saw. Recommended dosage is 320mg ed I believe.

 

[Anthony Roberts]

Pathologe. 2005 Nov;26(6):461-8.Click here to read Links
[Implications of estrogens and their receptors for the development and progression of prostate cancer]
[Article in German]

* Bonkhoff H,
* Fixemer T.

Praxis fur Pathologie, Berlin. [email protected]

The recent discovery of the estrogen receptors alpha and beta (ERalpha, ERbeta) and the progesterone receptor (PR) in human prostate tissue offers new insights into the role of estrogens and their receptors in prostate cancer development and tumor progression.The differentiation compartment of the prostatic epithelium (secretory luminal cells) expresses high levels of ERbeta, while the ERalpha is restricted to the proliferation compartment (basal cells). In high grade prostatic intraepithelial neoplasia (HGPIN), ERalpha gene expression extends to luminal cells and thus may mediate cancerogenic effects of estrogens on the dysplastic epithelium. Conversely, the ERbeta is downregulated in HGPIN indicating that the chemopreventive effects of phytoestrogens mediated by the ERbeta are partially lost. Irrespective of grades and stages, prostate cancer retains high levels of the ERbeta which is partially lost in androgen-insensitive stages of the disease. In contrast with breast cancer, the presence of the ERalpha and the PR is a late event in prostate cancer progression. At least 30% of metastatic and androgen-insensitive tumors express high levels of the PR indicating that these tumors harbor a functional ERalpha. The antiestrogen Raloxifene has growth-inhibitory effects on androgen-insensitive prostate cancer cells in vitro and induces the apoptotic cell death in a dose-dependent fashion. These data provide a rational for clinical trials to study the efficiency of antiestrogens in the medical treatment of advanced prostate cancer.

PMID: 16220300 [PubMed - indexed for MEDLINE]

 

[Mac173]

What cus my name isnt Tony, my info wasnt good enuff? I mean I made a quality post, why cant i get some love?

Did you write a book yet?

 

[ALIN]

every since i started popping 5-6 grams/day of SP, i don't have that uncomfortable stinging, tight feeling above my right nut, like its shrunk down a bit.

however, medical research is conflicting on this.

i think the reason conflicting medical reports is because big drug companies cant make money off saw palmetto