Excidium28 said:
My buddy had a question
"I am taking a blood pressure medication to regulate my blood pressure and keep it low. My blood pressure is currently around 135/60, which is a bit on the high side. How much will steroids cause it to elevate on average? What level is too high? Do some steroids cause it to increase more than others? If any, which ones should I avoid?"
pharmacist
there are 2 modes by which roids will elevate BP in your friend
the first is altering your salt balance, which will in turn alter how much fluid is in your body (mainly in your blood, and between your cells). since your bodys cardiovascular system is basically a set of pipes (blood vessels, veins, arteries) connected to a pump (your heart) with a limited amount of space within the pipes, the more fluid you try and jam into your blood vessels, the higher the pressure will go.
the second is that roids will increase muscle mass, whether in the short term (holding sugar + water + salt within the muscle, which is why a lot of lifters look pumped all the time when theyre 'on') or in the long term (ie more muscle tissue overall). the more muscle you have, the harder your heart has to push all that blood to get it through all that muscle tissue (imagine trying to squirt water from a hose through a sponge. same thing)
now. the answer to your question is "it depends".
it depends on how well your buddy controls his salt balance (by using anti aromatases, anti estrogens, limiting sodium). if he does it well, there may well be no impact on his BP via this mode. if he does it like shit, eats lots of salty stuff, drinks lots of booze, doesnt take his anti e's or anti aromatases, then his BP may skyrocket
now if your buddy is successful in weight training, he is going to put on muscle, and so the increase from mode 2 is going to happen one way or the other. in the short term, if he takes mega doses of roids, he will get a lot more sugar + salt + water in his muscles than if he takes lower doses. if he eats lots of protein, trains really hard, eats right etc then he is going to gain a lot of legit muscle, which is going to stay around after the roids cease. how much his BP will elevate via this mode will obviously depend on his doses, and success at gaining muscle.
thats teh best youre going to get, because youre not going to get a "dude, his systolic is going to increase by xyz millimetres murcury and his diastolic will increase by abc millimetres murcury" from anyone who either knows wtf they are talking about or isnt a liar.
personally i view his 135 systolic as being a tad high for my liking. if i had a patient on medication who was still at 135, i would by tweaking or throwing in other drugs to drop it a bit more. im also not a fan of his 65 diastolic compared to his high-ish systolic, since you tend to get more problems when there is a big difference between the two pressures. i dont expect taht everyone have 120/80 as per the mid literature, but i like them to be similar, and low. less bullshit happens that way.
it would be interesting to know what kind of BP medication he is on.