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Provizan-15

Catch Wrestler

New member
Can anyone tell me if Provizan-15 is any good as a fat burner??It is also known as Sibutramine hydracloride.Another name for it is meridia.What can you tell me about it,and how would you compare it to other fat burners??Mostly interested to here from people who have actually used it.
Thanks.
 
Although Meridia and fenfluramine have similar mechanisms of action (they both affect serotonin), fenfluramine boosts the levels of serotonin into the blood stream. This increase in the levels of serotonin is believed to have caused the heart valve damage seen in some patients. Essentially the difference between the two drugs is that Meridia is more localized, whereas fenfluramine has a systemic effect. Because of this difference, researchers believe that Meridia will not be linked with heart valve damage. As stated by Lawrence Cheskin, M.D., director of the Johns Hopkins Weight Management Center in Baltimore, "Meridia bypasses the heart and acts directly on the brain’s appetite control center. Meridia maintains serotonin levels in the brain, thereby curbing some carbohydrate cravings (Brietzke, 90)". Carbohydrates boost levels of serotonin in the brain, and this impacts appetite and mood so when your brain is running low on the chemical, it tells you to refuel. Meridia keeps serotonin levels elevated, short-circuiting these mentally fueled cravings. The drug also boosts adrenaline levels, curbing overall appetite.

Side Effects
Though Meridia may be safer than other anti- obesity drugs, it still warrants caution. The most troubling side effects include increase in blood pressure, heart rate, and abnormal heart rhythms (arrythmias) seen in some participants during clinical trials. However, most of these side effects were observed in participants who took large doses (more than 15 mg) of the drug (Portyansky, 23). Blood pressure elevations were controlled in these trials with dose adjustments . Those who do have high blood pressure to begin with are urged to weigh the benefits and risks of taking this drug. Meridia’s labeling recommendations calls for blood pressure and pulse measurements prior to therapy initiation and regular monitoring thereafter for all patients. For more information on the increase in blood pressure and heart rate go to www.4meridia.com/hcprof/fsa.htm on the world wide web. The most commonly reported side effects include dry mouth, headache, constipation, and insomnia, "but people seem to find these effects pretty tolerable", according to Cornell Medical Center’s Dr. Louis Aronne (Anonymous, 98).

Personally m8 I would stay away from it. Havent heard any good things about it, diet cardio then clen and eph, would be a lot better.
 
I like meridia, always use it for a few months in the spring. Help me stay my diet. Works well for 6-8 weeks, after that you start to notice a dimminished effect.
 
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