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fallenangel
New member
here's a post on prostrate enlargment i lifted from muscletalk.co.uk i think it interesting espiecially the point about prostrate size returning to almost baseline levels after the discontiation of aas use.
Many of the side effects of these steroids are well documented but little is known of the possible effects of long term abuse on the androgen sensitive prostate gland and the potential adverse consequences on urinating patterns(hence the title of this post!)
Androgens are necessary not only for the development of the prostate,but the maintenance of morphology,cell number and functional activity of the adult gland.The prostate sits underneath the bladder and if enlarged can block the urine outflow from the bladder making it difficult to pass urine.
Even in Dan Duchaines Underground Steroid Handbook it states that "Usually prostate enlargement happens when men use very androgenic steroids, and not necessarily high dosages of such steroids"
Lets look at the evidence.
Firstly,previous animal studies(rodents)have shown that the administration of exogenous testosterone esters results in an increase in prostatic volume but that subsequent steroid withdrawal is accompanied by a reduction in volume to pretreatment levels.
A report in 1972 suggested an association between use and voiding dysfunction.They studied 10 guys using D/bol and one experienced urinary frequency and discomfort on micturition.
One of the major studies is a double-blind trial of the effects of oral testosterone undecanoate on prostate volume in eugonadal middle aged men.There results showed that there was an increase in mean prostate volume by 12%,however there was no difference in voiding pattern.
The final and important study was that on a bodybuilder who was doing a seven week course and routinely using AS in the past.
The results revealed an increase in prostatic volume by almost 52% and flow rate also decreased.After 4 weeks post cycle the values came back near the baseline values but not exactly normal.
The man also noted an increase in going to the toilet and urinating during the night(twice as compared to normally none)
The reason why the previous study which showed a 12% increase in prostate volume but no change in urinating pattern was because they just gave a single steroid while the BBer in the second study was cycling three steroids(dosages were no more than 690mg per week total)
In summary we can conclude that AS does cause prostatic enlargement and this can occur with moderate dosages,with the length of usage being a variable factor.
Good point is that the effects are reversible after several weeks if the course is stopped.
On a personal level this is an interesting topic since I have just finished a urology job and discussed this topic with my colleague who is a consultant urological surgeon.
We are both of the opinion that the prostatic enlargement happens in everyone.
However the degree of enlargement varies from person to person and this will determine whether or not you experience any urinary symptoms.The risk is that if severe enough you can go into urinary retention (which along with renal stones are two of the most painful conditions a bloke can go through!)
The problem with these studies is of the low number of participants which doesnt give an accurate result.
So lets do our own survey,how many of the members have experienced any urological symptoms on AS use?
The symptoms to look out for are:
1) Hesistancy:having to wait for the urine to start flowing.
2)Poor stream:urine flows with less force,travelling a short distance.
3)Terminal dribbling:Spurts or dribbles after the main stream has finished.
4)Incomplete emptying:there is a feeling that there is still urine in the bladder after urination has finished.
5)Frequency:going more often to urinate.
6)Nocturia:going more often during the night to urinate.
7)Urgency:Unable to hold on after feeling the need to pass urine.
8)Dysuria:discomfort passing urine(usually means an infection)
Many of the side effects of these steroids are well documented but little is known of the possible effects of long term abuse on the androgen sensitive prostate gland and the potential adverse consequences on urinating patterns(hence the title of this post!)
Androgens are necessary not only for the development of the prostate,but the maintenance of morphology,cell number and functional activity of the adult gland.The prostate sits underneath the bladder and if enlarged can block the urine outflow from the bladder making it difficult to pass urine.
Even in Dan Duchaines Underground Steroid Handbook it states that "Usually prostate enlargement happens when men use very androgenic steroids, and not necessarily high dosages of such steroids"
Lets look at the evidence.
Firstly,previous animal studies(rodents)have shown that the administration of exogenous testosterone esters results in an increase in prostatic volume but that subsequent steroid withdrawal is accompanied by a reduction in volume to pretreatment levels.
A report in 1972 suggested an association between use and voiding dysfunction.They studied 10 guys using D/bol and one experienced urinary frequency and discomfort on micturition.
One of the major studies is a double-blind trial of the effects of oral testosterone undecanoate on prostate volume in eugonadal middle aged men.There results showed that there was an increase in mean prostate volume by 12%,however there was no difference in voiding pattern.
The final and important study was that on a bodybuilder who was doing a seven week course and routinely using AS in the past.
The results revealed an increase in prostatic volume by almost 52% and flow rate also decreased.After 4 weeks post cycle the values came back near the baseline values but not exactly normal.
The man also noted an increase in going to the toilet and urinating during the night(twice as compared to normally none)
The reason why the previous study which showed a 12% increase in prostate volume but no change in urinating pattern was because they just gave a single steroid while the BBer in the second study was cycling three steroids(dosages were no more than 690mg per week total)
In summary we can conclude that AS does cause prostatic enlargement and this can occur with moderate dosages,with the length of usage being a variable factor.
Good point is that the effects are reversible after several weeks if the course is stopped.
On a personal level this is an interesting topic since I have just finished a urology job and discussed this topic with my colleague who is a consultant urological surgeon.
We are both of the opinion that the prostatic enlargement happens in everyone.
However the degree of enlargement varies from person to person and this will determine whether or not you experience any urinary symptoms.The risk is that if severe enough you can go into urinary retention (which along with renal stones are two of the most painful conditions a bloke can go through!)
The problem with these studies is of the low number of participants which doesnt give an accurate result.
So lets do our own survey,how many of the members have experienced any urological symptoms on AS use?
The symptoms to look out for are:
1) Hesistancy:having to wait for the urine to start flowing.
2)Poor stream:urine flows with less force,travelling a short distance.
3)Terminal dribbling:Spurts or dribbles after the main stream has finished.
4)Incomplete emptying:there is a feeling that there is still urine in the bladder after urination has finished.
5)Frequency:going more often to urinate.
6)Nocturia:going more often during the night to urinate.
7)Urgency:Unable to hold on after feeling the need to pass urine.
8)Dysuria:discomfort passing urine(usually means an infection)
