Always, because I'm very sensitive for test. Saw palmetto is the basic, but always take something more complex. Like: zinc, pumpkin seed oil, uva-ursi extract.
Mechanism of Action
The mechanism of action is antiandrogenic. Studies have shown that a liposterolic extract of the berries reduced the uptake by tissue specimens of both testosterone and DHT(dihydrotestosterone) by more than 40%. This mechanism is confirmed by the observation that saw palmetto extract does not induce changes in the level of testosterone or other hormones in the plasma itself. Other studies have noted that it reduces the conversion of less active testosterone to the more active DHT by inhibiting the enzyme steroid 5 alpha reductase. In addition to their antiandrogenic properties, anti-inflammatory and antiedematous activities have all been demonstrated in the berries. This apparently results from inhibition of the cyclooxygenase and 5-lipoxygenase pathways thereby preventing the biosynthesis of inflammation-producing prostaglandins and leukotrienes.