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propecia and eq
- Thread starter tiny5
- Start date
works fine with eq
BOldenone is not 5-alpha reduced in the human body to any appreciable degree at all. Propecia is of no relevance.
- Bill Llewellyn
- Bill Llewellyn
Silent Method
New member
Bill, I've seen other posts saying that EQ is directly comparable to testosterone in side effects and the mechanism of those side effects. Whats the real story? What sides can one get from EQ, and by what mechanism do these sides occur?
Stan O'Zolol
New member
I agree with W_Llwellyn.
Silent Method
New member
bump
solidspine
New member
I have never lost any hair from EQ, and have used propecia with good results, now I simply keep my hair super short, not bald, just super short. Got tired of taking those 1 dollar pills everyday.
Silent Method said:
All androgenic side effects occur via androgen receptor stimulation. All AAS activate this receptor, and all potentially cause such side effects. T is a more potent androgen than most agents of course because it is reduced via 5-alpha reductase to DHT (a more potent steroid) in many androgen target tissues. Although a 5-alpha reduced version of boldenone (1-testosterone actually) is a more potent activator of the AR than boldenone, boldenone also has an extremely LOW affinity for 5-AR. 99.8% of the dihydro metabolites are relatively inactive 5-beta's. There are virtually no 5-alpha metabolites of boldenone found in humans. This is why Propecia, which inhibits 5AR, can lower the androgenic nature of T but not of boldenone.
- Bill Llewellyn
Silent Method
New member
What is the difference between "a 5-alpha reduced version of boldenone" and boldenone? Or have I misread this point? Does EQ target a particular mechanism(s) of hair loss and acne, and to what degree? If so, what, if any, androgen receptor inhibitor (or other drugs) would be effective against boldenone side effects?
pa1ad said:
Have fun Bill!!
Thanks Pat!
I’ll try a more succinct explanation in a couple of minutes… as soon as the dizziness subsides from repeatedly hitting my head against the desk.
- Bill
Silent Method
New member
Thanks guys - you make me feel good about me!
I reread your explination and it made more sense to me. (No really, it did.)
I'll pose a more succinct question - Will boldenone fuck with your hair in other ways? If so, is their an anti-androgenetic drug that can help?
Silent Method said:
My answer to this is that all androgenic/anabolic steroids have the potential to cause male pattern baldness. However, since boldenone and its metabolites are not strongly androgenic, or related to DHT in any way, it probably is one of the milder steroids out there in regards to hairline.
BTW, we still don't really know if steroid's attacking of the hairline is just do to an androgen receptor mediated mechanism or if there is something unique about DHT that enables it to initiate some unique mechanism that is yet to be identified.
Silent Method
New member
So we've determined that 5AR doesn’t touch EQ. Either boldenone flat out doesn’t touch your hair, or adverse effects regarding steroids and hair are at least partially androgen receptor mediated. I vote for the later. As Bill said, "all androgenic side effects occur via androgen receptor stimulation."
So whats the deal? Does boldenone fuck with your hair or not? From what I've gathered it does to some extent, so would a drug that inhibits androgen reception in the scalp (which we have determined finastride does not do) help?
Bill, you think up that concise answer yet?
pa1ad said:
ONe more thing. In women at least, stanozolol ( a DHT derivative) seems to promote alot more hair loss then would be predicted by its androgenic potency. This suggests the possibility of non-androgenic mediated promotion of MPB by DHT and some of its derivatives
Silent Method
New member
Great points pa1ad.
pa1ad said:
Pat correctly points out that there is a lot about the activity of steroids that we do not know for certain. Although they are known to work largely via the cellular androgen receptor, other modes of action are likely to exist. With our lack of full understanding about this subject I would concede that this might possibly include the way androgens affect hair loss.
That said, I also think the fact that hair loss has been noted with a wide variety of steroids, and not just with testosterone or DHT based compounds, says a lot. I really support the notion that DHT is not unique in regards to its ability to promote MPB, and it is simple androgen receptor stimulation in the scalp that is to blame. That would mean that all AAS, given the right genetics and level of activity in the scalp (dosage), could potentially trigger MPB. Whether you ascribe to this or not, certainly you shouldn’t let the fact that a steroid is not a derivative of DHT lull you into a false sense of security.
- Bill Llewellyn
