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pituitary shrinkage from using GH, case study

Sigmund Roid

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This article is in favor of using GH 5 days on 2 days off, and avoiding administration right before bed. Be careful bros!


Neurol Res 2001 Jun;23(4):336-8 Related Articles, Links


Secondary partial empty sella syndrome in an elite bodybuilder.

Dickerman RD, Jaikumar S.

National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Surgical Neurology Branch, Bethesda, MD, USA. [email protected]

The pituitary gland is a hormone-responsive gland and is known to vary in size depending on the hormonal status of the patient and the multifaceted positive and negative feedback hypothalamic-pituitary-gonadal axis. Partial empty sella syndrome with an atrophied pituitary gland is seen in primary neuroendocrinopathies such as growth hormone deficiency, primary hypothyroidism, central diabetes insipidus and hypogonadism. Partial empty sella has also been shown to occur in patients with elevations in intracranial pressure. Secondary partial empty sella syndrome with significant pituitary gland atrophy from negative feedback inhibition of long-term exogenous hormonal use has not been previously reported. We are reporting on a case of partial empty sella syndrome occurring in an elite bodybuilder with a long history of exogenous abuse of growth hormone, testosterone and thyroid hormone. The pathophysiological mechanisms of secondary partial empty sella syndrome from exogenous hormone use and the possibility for elevations in intracranial pressure contributing to this syndrome will be discussed.

PMID: 11428511 [PubMed - indexed for MEDLINE]
 
Strange hearing that . I have Diabetes insipudus. My pitutary is virtualy non-existant( tumor is located on the stalk going into hypothylamus). I have been on HGH for about 10 months now.Plus Testosterone. I'm going to write our good friend The Dr. and discuss it with him.
 
Yeah, real odd you mention that... I have several friends who do competitions and they use GH in the morning at at night before bed, and if they HAD to choose, they'd use at night... something about better time to use it then, as your natural GH levels are higher in the daytime??

C-ditty
 
Your body has to grow and at night while your sleeping is the best time. I take HGH shots in after 3:00 ,then while I'm sleeping it can do it's thing. I met with people from Upjohn when I first started taking HGH . They told me take the shot late afternoon. It works best!
 
According to my fysiology book you have to have both GH and insulin in your system for anabolic processes. In the night the insulin level is low, and you cannot use slin of course. This is why I use it upon waking up and 30 minutes before the end of my training, together with insulin.
 
i have a ademona (sp?) tumor on my pituitary. they say 70% of the population have it. anway, after 6 months of GH, the size of the tumor decreased just a little. i didn't tell doc about the GH though. i originally had to get MRI's done every 6 months, but since the decrease in size, they made it annually.
 
i was about to start a 5 on 2 off GH & test cycle. i had planned an AM shot of 2iuGH and 10units of slin together, then 2 iu of GH pre work out and 10 units slin post workout, with one amp of sust each day. would i be better to just do the 4iu GH per work out and 10 units slin post? i had not considered doing the GH before bed. opinions...
 
From what i've read GH injections take som time before it peaks. So GH pre workout and insulin post workout is supposed to the best/////


just my .02
 
so it's better to skip the AM shot and use a higher dose at the pre workout shot? i am not looking for huge gains from this first cycle of GH, but i want to be sure not to waste it, or use too little to heal my joints... i could do a GH in the AM before some cardio, then slin after...then GH per workout and slin after as long as it dosent get too late???
 
Sigmund Roid said:
This article is in favor of using GH 5 days on 2 days off, and avoiding administration right before bed. Be careful bros!
You cant just read something like this and run around yelling the sky is falling. For example, look at this section of the above abstract.

Secondary partial empty sella syndrome with significant pituitary gland atrophy from negative feedback inhibition of long-term exogenous hormonal use has not been previously reported. We are reporting on a case of partial empty sella syndrome occurring in an elite bodybuilder with a long history of exogenous abuse of growth hormone, testosterone and thyroid hormone.

1st off, how long is LONG-TERM? Secondly this guy was an elite bodybuilder, not your average weekend warrior. Its pretty hard for any of us to take any info in the posted abstract and apply it to us since the information supplied is not specific.
 
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