chris69 said:
You might have already seen this artical, Also check out last sticky, good info

HCG - human chorionic gonadotropin - after cycle, Some say start last week of cycle..Lots of post on this shit, read up and deside what you want to try IMO.Thats what i have done, theres just so many opinions Bro.
Using HCG - human chorionic gonadotropin -
It is our opinion that HCG - human chorionic gonadotropin - is probably one of the most misunderstood and misused compounds in bodybuilding. Hopefully this information will go some way towards rectifying that for the members of MuscleTalk. HCG stands for Human Chorionic Gonadotrophin and is not a steroid, but a natural peptide hormone which develops in the placenta of pregnant women during pregnancy to controls the mother's hormones. (Incidentally, this is the reason you may hear of people testing for growth hormone (human growth hormone - somatropin - ) with a pregnancy testing kit - If their HGH shows 'pregnant', they've been ripped-off with cheaper HCG - but we digress slightly).
Its action in the male body is like that of lh - leutenizing hormone - , stimulating the Leydig cells in the testes to produce testosterone even in the absence of endogenous LH. HCG - human chorionic gonadotropin - is therefore used during longer or heavier steroid cycles to maintain testicular size and condition, or to bring atrophied (shrunken) testicles back up to their original condition in preparation for post-cycle Clomid therapy. This process is necessary because atrophied testicles produce reduced levels of natural testosterone, this situation should be rectified prior to post-cycle Clomid therapy.
HCG - human chorionic gonadotropin - administration post-cycle is common practice among bodybuilders in the belief that it will aid the natural testosterone recovery, but this theory is unfounded and also counterproductive. The rapid rise in both testosterone, and thus oestrogen due to aromatisation, from the administration of HCG causes further inhibition of the hpta - hypothalamic-pituitary-testicular axis - (Hypothalamic/Pituitary/Testicular Axis - feedback loop discussed above); this actually worsens the recovery situation. HCG does not restore the natural testosterone production.
The typically observed dosing of 2000 to 5000IU every 4 to 5 days causes such an increase in oestrogen levels via aromatisation of the natural testosterone that this has been responsible for many cases of gynecomastia.
From the above discussion it is clear that HCG - human chorionic gonadotropin - is best used during a cycle, either to:
1) Avoid testicular atrophy, or
2) Rectify the problem of an existing testicular atrophy.
Doses of HCG - human chorionic gonadotropin -
Smaller doses, more frequently during a cycle will give best overall results with least unwanted side effects. Somewhere between 500iu and 1000iu per day would be best over about a two-week period. These doses are sufficient to avoid/rectify testicular atrophy without increasing oestrogen levels too dramatically and risking gynecomastia. This dosing schedule also avoids the risk of permanently down-regulating the lh - leutenizing hormone - receptors in the testes.
Presentation and Administration of HCG - human chorionic gonadotropin -
Synthetic HCG - human chorionic gonadotropin - is often known as Pregnyl (generic name) and is available in 2500iu and 5000iu (not ideal for the above doses!). Administration of the compound is either by intra-muscular or subcutaneous injection. It comes as a powder which needs to be mixed with the sterile water. The powder is temperature-sensitive prior to mixing and should not be exposed to direct heat. After mixing, it should be kept refrigerated and used within a few weeks - though there are sterility issues which need to be considered after mixing.
Summary and Price of Clomid and HCG - human chorionic gonadotropin -
Clomid is more effective than HCG - human chorionic gonadotropin - post cycle, but some long-term users like to use HCG during a cycle, or to prepare the testes
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