Most c-17aa's are piss poor A/R binders/activators,yet they still illicit profound effects on muscle size.As an example,dianabol has odd anabolic(additive)capabilities in that it greatly increases potassium/calcium synthesis,and prevents calcium leaks from muscle cells.Calcium is quite an important nutrient for cellular function/contractile activity.Halo,d-bol,and oxandrolone have been shown to have high affinities for mitochondria,which is non-A/R related,but has far reaching capabilities where energy/ATP is concerned.