Every day. I've heard way too many people say they tried 150 EOD and got no response, but went to 75 ED and started seeing results. This may be because it took a while to start kicking in, and they didn't wait long enough to feel 150 EOD.
Just to be safe, I am taking 75/day of my homebrew. The only difference to me is that it probably keeps tren levels more consistent in my body, which is always a good thing, even though there are twice the injections.
Plus if you are site injecting then I think ED is better so you rotate through different sites faster. I really don't see the point of EOD unless you have seen results from it before, or you don't like poking yourself.