The story is takes place during WWII. Joe Kavalier is a Jew from Prague that escapes to New York to live with his cousin Sam Klayman. Here's the review from Amazon:
Like the comic books that animate and inspire it, The Amazing Adventures of Kavalier & Clay is both larger than life and of it too. Complete with golems and magic and miraculous escapes and evil nemeses and even hand-to-hand Antarctic battle, it pursues the most important questions of love and war, dreams and art, across pages brimming with longing and hope. Samuel Klayman--self-described little man, city boy, and Jew--first meets Josef Kavalier when his mother shoves him aside in his own bed, telling him to make room for their cousin, a refugee from Nazi-occupied Prague. It's the beginning, however unlikely, of a beautiful friendship. In short order, Sam's talent for pulp plotting meets Joe's faultless, academy-trained line, and a comic-book superhero is born. A sort of lantern-jawed equalizer clad in dark blue long underwear, the Escapist "roams the globe, performing amazing feats and coming to the aid of those who languish in tyranny's chains!" Before they know it, Kavalier and Clay (as Sam Klayman has come to be known) find themselves at the epicenter of comics' golden age.
But Joe Kavalier is driven by motives far more complex than your average hack. In fact, his first act as a comic-book artist is to deal Hitler a very literal blow. (The cover of the first issue shows the Escapist delivering "an immortal haymaker" onto the Führer's realistically bloody jaw.) In subsequent years, the Escapist and his superhero allies take on the evil Iron Chain and their leader Attila Haxoff--their battles drawn with an intensity that grows more disturbing as Joe's efforts to rescue his family fail. He's fighting their war with brush and ink, Joe thinks, and the idea sustains him long enough to meet the beautiful Rosa Saks, a surrealist artist and surprisingly retrograde muse. But when even that fiction fails him, Joe performs an escape of his own, leaving Rosa and Sammy to pick up the pieces in some increasingly wrong-headed ways.
It's an incredible book - I had a hard time putting it down.
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