Need help for Estradiol WAY too high

[morphi]

I'm a long-time reader but first time poster (and juicer). I started TRT (with a doctor). After trying Test. cream for a while, he moved me to weekly injections of 200 mg Test. (180 mg cyp + 20 mg prop). I took the Test. home for self-injections. He said I could increase the dose (to 300mg) after a few weeks if I felt like it. Here is what I have injected so far:

5/31/12: 200 mg
6/4/12: 250 mg
6/11/12: 300 mg

BEFORE my latest injection on 6/11 I had blood drawn and got the results back the next day. There was good news and bad news.

Total Test. Serum: >1,500 ng/dL (range: 348-1197)
Estradiol: 102.6 pg/mL (range: 7.6-42.6)
LH: 8 (range: 1.1-8.6)

Remember the blood was drawn 7 days since my last injection. Later that day, I would inject again for that week.

During this time, I have taken 1mg anastrozole and 40mg Nolvadex every day. (Until yesterday, my anastrozole was underground and so may not be legit or dosed correctly. Now I take Arimidex.)

I'm happy with the Test. level but concerned about the Estradiol. I have gained water weight. I would think the Arimidex+Nolvadex in high doses would have kept estradiol from getting so high. So my question to you guys is…

What more can I do to lower my estradiol levels?

I'm not trying to bulk up. I want to cut. Test. may not be the best for cutting, but it's all I had (legal) access to so I had to go with it. I now also take T4 and albuterol every day. I might add Bromo next week.

 

[auslifter90]

There's no way you should have so much estrogen on 1mg of adex from the injections you were given, I'm guessing your gear was fake or just underdosed.

 

[morphi]

I hope you are right about the underground AI being illegit. Otherwise I'm baffled how the E could be so high.

Now that I have pharmacy-grade Arimidex, I will cut back to 0.5mg EOD.

Should I re-test next week to see if the REAL Arimidex has helped lower E? Or is that too soon?

 

[rage22]

Take this for what its worth. Im new to injections but Im on my 3rd shot of test cyp today @ 150mg per shot (300mg ew) and I started taking arimidex right away .25mg eod and I'm already having a little joint soreness. So I think you should be able to feel the effectiveness of the AI pretty quickly. And just to be sure, I'd get another blood test.

 

[morphi]

REAL Arimidex seems to be working. My first blood test on June 11 (after 2.5 weeks on Test Cyp+Prop 200-300mg/wk) was:

Total Test: +1500 (range 348-1197)
Estradiol: 102.6 (range 7.6-42.6)
LH: 8.0 (range 1.7-8.6)

Over the next week I took 4mg Arimidex spread over 7 days. On June 18, my numbers were:

Total Test: +1500 (range 348-1197)
Estradiol: 16.6 (range 7.6-42.6)
LH: 9.1 (range 1.7-8.6)

A few questions:

What level of Estradiol should I be trying to maintain? I plan on taking 1/2mg Arimidex EOD for the next week and have another test on June 25.

Also, does the rise in LH (to above range) mean that I am avoiding HPT suppression/shutdown so far?

 

[stevesmi]

why are you even on HRT with those LH numbers?

wow just wow. you have a very strong HPTA and you are gonna throw all that away to go on HRT for life? why??!!

yes your LH is gonna be at 0 within a couple months. the fact you would even ask this question means you haven't done enough homework to make probably the biggest decision of your life and your doctor is just after your money and did not explain the consequences.

you better re think this decision again, you still have time to stop what you are doing. and you can just save the script and keep the vials for future cycles.. you don't have to go on HRT

 

[morphi]

Thank you for your concern Steve. I do not plan to be on HRT for life. I've recently gotten my doctor to put me on injectible Test so I started my first "cycle". After this cycle is done, I plan on stock-piling the Test. for future cycles. Hopefully keeping the cycles short and low-dose and using anti-Es/AIs during the cycle and having a good PCT will mean I can keep my HPTA healthy over the long term.

My Test. levels were in the mid-300s before the Test. injections. I am doing an aggressive diet and wanted the Test. boost to ensure I did not loose too much lean mass. But the focus is still on fat loss.

 

[ALIN]

There's no way you should have so much estrogen on 1mg of adex from the injections you were given, I'm guessing your gear was fake or just underdosed.

No way the gear is fake with those levels. You need to swich AI's.
I would use LETROZOLE in this situation if it were me. 1.25mg EOD.

 

[morphi]

No way the gear is fake with those levels. You need to swich AI's.
I would use LETROZOLE in this situation if it were me. 1.25mg EOD.

I was thinking that my original anastrozole (underground) was fake/underdosed considering I was on it for quite some time at a high dose when my Estradiol levels came back very high (102.6).

Over the next week, I started using pharmacy-grade anastrozole (4mg over seven days) and my Estradiol level went down to 16.6.

What "gear" were you referring to not being fake given my test results: the Test. or the anastrozole? (I know the Test. isn't fake. It came from my Dr.) If you meant that my anastrozole wasn't fake, what part of my test results indicates that?