Please Scroll Down to See Forums Below 
Nolvadex Question
Well I've been cruising your board for sometime and its a great board with ALOT of information and I'm glad to now be apart of it. Here is my first question, based on the study I'm going to post below 20 of tamoxifen is comparable to 150mg/day of clomiphene citrate...so does this mean that 20mg of tamoxifen would be more effective than 50-100mg of clomiphene citrate? I seem to have better results using nolvadex post-cycle than clomid and I'm wondering if I would great better results with clomid if I used 150mg of clomid...
Fertil Steril 1978 Mar;29(3):320-7 Hormonal effects of an antiestrogen, tamoxifen, in normal and oligospermic men. Vermeulen A, Comhaire F
The administration of tamoxifen, 20 mg/day for 10 days, to normal males produced a moderate increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of clomiphene citrate (Clomid). However, whereas Clomid produced a decrease in the LH response to LH-releasing hormone (LHRH), no such effect was seen after the administration of tamoxifen. In fact, prolonged treatment (6 weeks) with tamoxifen significantly increased the LH response to LHRL. Treatment of patients with "idiopathic" oligospermia for 6 to 9 months resulted in a significant increase in gonadotropin, testosterone, and estradiol levels. A significant increase in sperm density was observed only in subjects with oligospermia below 20 X 10(6)/ml and normal basal FSH levels. When basal FSH levels were increased or oligospermia was moderate (greater than 20 X 10(6)/ml); no effect on sperm density was seen. As sperm density increased, FSH levels decreased, suggesting an inhibin effect. Sperm motility was not improved by tamoxifen treatment. In five boys with delayed puberty, tamoxifen treatment appeared to activate the pituitary-gonadal axis and pubertal development.
Well I've been cruising your board for sometime and its a great board with ALOT of information and I'm glad to now be apart of it. Here is my first question, based on the study I'm going to post below 20 of tamoxifen is comparable to 150mg/day of clomiphene citrate...so does this mean that 20mg of tamoxifen would be more effective than 50-100mg of clomiphene citrate? I seem to have better results using nolvadex post-cycle than clomid and I'm wondering if I would great better results with clomid if I used 150mg of clomid...
Fertil Steril 1978 Mar;29(3):320-7 Hormonal effects of an antiestrogen, tamoxifen, in normal and oligospermic men. Vermeulen A, Comhaire F
The administration of tamoxifen, 20 mg/day for 10 days, to normal males produced a moderate increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of clomiphene citrate (Clomid). However, whereas Clomid produced a decrease in the LH response to LH-releasing hormone (LHRH), no such effect was seen after the administration of tamoxifen. In fact, prolonged treatment (6 weeks) with tamoxifen significantly increased the LH response to LHRL. Treatment of patients with "idiopathic" oligospermia for 6 to 9 months resulted in a significant increase in gonadotropin, testosterone, and estradiol levels. A significant increase in sperm density was observed only in subjects with oligospermia below 20 X 10(6)/ml and normal basal FSH levels. When basal FSH levels were increased or oligospermia was moderate (greater than 20 X 10(6)/ml); no effect on sperm density was seen. As sperm density increased, FSH levels decreased, suggesting an inhibin effect. Sperm motility was not improved by tamoxifen treatment. In five boys with delayed puberty, tamoxifen treatment appeared to activate the pituitary-gonadal axis and pubertal development.
Last edited:
