Even tightening of the skin has been reported. If there are no known side effects aside from rats. I'm really wanting to test this out for long cycles.
http://www.toxicology.org/AI/Pub/Tox/2009Tox.pdf
If you search the document for 501516 and PPAR, you'll find a number of articles that basically say two things:
1. PPAR-delta agonism, GW-501516 in particular seems to cause cancer throughout the body at doses 100-1000x the typical dose.
2. COX-2 inhibition is useful to prevent it.
It's definitely cheaper than HGH by a huge margin. Studies have proven that the peptide is essentially "exercise in a pill" with the physiological responses is triggers.
Pretty fascinating stuff, but the toxicology reports horrify me.
See NIH's data for GW501516
That is at doses higher than most users, but not hugely so... the effect was seen with doses as low 5mg/kg.
The only similar alternative is Telmisartan, an Angiotensin receptor type-2 antagonist.. Telmisartan is also a PPAR-gamma agonist.
Supposedly, Telmisartan causes similar results with *far* less toxicity... and of course WADA banned it last year.
5mg/kg is a HUGE dose. The dose that most use here is 10-20mg a day. For a 200 pound guy, a dose of 5mg/kg would be 455mg a day!!!
You're absolutely right. There are plenty of people taking 40-60mg/day too. Still, under the studied amount but the carryover to risk at low dose is not studied (or was well hidden by GlaxoSmithKline). Even at an order of magnitude less dosage, risks should be considered carefully. From my perspective, GW makes even tren look like a multi-vitamin in risk factor.
Cancer? Please excuss my lack of education on tren but I have not seen any studies that show tren causes cancer.
Please post them if you have them.
Sorry, I wasn't implying that! I just meant that the dangers of GW make trenbolone's side effects appear pretty laughable.
Both companies are sponsors, they're both good places...I've just made a home at SS while you've done the same with Unique.As PSizzle said, GW is the bomb (paraphrasing). Sarmssearch is certainly a great company. I've used Uniquemicals with fantastic success and stand by their products - just finished a killer cycle running the triple stack of GW, S4 and Osta and it was amazing.
Both companies are sponsors, they're both good places...I've just made a home at SS while you've done the same with Unique.![]()
I disagree. Like the study stated, 100-1000 times the typical dose showed signs of cancer. So, don't do that. What do you think 100-1000 times the typical dose of anything would do? OTC supps? Milk? Oranges? Tren? Prob not a good thing. Most of everything can be safe in moderation
Sorry, I wasn't implying that! I just meant that the dangers of GW make trenbolone's side effects appear pretty laughable.
5mg/kg is a HUGE dose. The dose that most use here is 10-20mg a day. For a 200 pound guy, a dose of 5mg/kg would be 455mg a day!!!
This is probably a dumb question, but are these compounds (osta, s4, GW) sensible in a stack w test, etc? In other words, should I wait until my rodents are between cycles to use these compounds?
anyone ever run GW with a test cycle?
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