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mesotherapy

it works great, check out the plastic surgery section here, more info.

make sure that the dr. doesnt use pre filled, or pre mixed solutions.

make sure they mix it in the office.

the premixed concoction is bad news, since the ppc has a high ph, and some of the other ingredients are sensitive, expire in 30 days once mixed etc.....

so as long as you go to a reputable dr. then all is good, and she will love the results.
 
jeepboi said:
it works great, check out the plastic surgery section here, more info.

make sure that the dr. doesnt use pre filled, or pre mixed solutions.

make sure they mix it in the office.

the premixed concoction is bad news, since the ppc has a high ph, and some of the other ingredients are sensitive, expire in 30 days once mixed etc.....

so as long as you go to a reputable dr. then all is good, and she will love the results.
Click to expand...
k+ thanks
 
the active ingredient is deoxycholate. its works like a DETERGENT. It causes cell lysis. This cell lysis is INDISCRIMINATE. Can kill both fat and muscle cells.

IMO it should be used with great care and long term effects have not been evaluated.

phosphatidyl choline does not have any activity of its own, it may augment delivery of the deoxycholate but that remains to be seen. (ie other bases tried)
 
macrophage69alpha said:
the active ingredient is deoxycholate. its works like a DETERGENT. It causes cell lysis. This cell lysis is INDISCRIMINATE. Can kill both fat and muscle cells.

IMO it should be used with great care and long term effects have not been evaluated.

phosphatidyl choline does not have any activity of its own, it may augment delivery of the deoxycholate but that remains to be seen. (ie other bases tried)
Click to expand...


thats why the PPC/DC phosphatidylcholine has deoxycholic acid in it. generally 5/4.2 or 10/8.4 BUT, Collegenase, Artichoke, Aminophyline, Some procaine, and somewhat new to meso is they are adding HGH to it.

Also it is injected into the derm layer, so you dont have necrosis etc...
 
macrophage69alpha said:
the active ingredient is deoxycholate. its works like a DETERGENT. It causes cell lysis. This cell lysis is INDISCRIMINATE. Can kill both fat and muscle cells.

IMO it should be used with great care and long term effects have not been evaluated.

phosphatidyl choline does not have any activity of its own, it may augment delivery of the deoxycholate but that remains to be seen. (ie other bases tried)
Click to expand...
there has to be a study out on this
 
NYBodyguard said:
there has to be a study out on this
Click to expand...

Dermatol Surg. 2006 Apr;32(4):465-80. Related Articles, Links


Mesotherapy and phosphatidylcholine injections: historical clarification and review.

Rotunda AM, Kolodney MS.

Department of Dermatology, University of Southern California School of Medicine, Los Angeles, California, USA. [email protected]

BACKGROUND: Mesotherapy was originally conceived in Europe as a method of utilizing cutaneous injections containing a mixture of compounds for the treatment of local medical and cosmetic conditions. Although mesotherapy was traditionally employed for pain relief, its cosmetic applications, particularly fat and cellulite removal, have recently received attention in the United States. Another treatment for localized fat reduction, which was popularized in Brazil and uses injections of phosphatidylcholine, has been erroneously considered synonymous with mesotherapy. Despite their attraction as purported "fat-dissolving" injections, the safety and efficacy of these novel cosmetic treatments remain ambiguous to most patients and physicians. OBJECTIVE: To distinguish mesotherapy from phosphatidylcholine injections by reviewing their history and the relevant experimental or clinical findings. METHODS: A comprehensive search of Medline indexed literature and conference proceedings. RESULTS: All the published studies evaluating the clinical efficacy of traditional mesotherapy currently originate from Europe. These reports focus primarily on musculoskeletal pain and vascular disease, rather than cosmetic applications. Although experimental data suggest that a number of traditional mesotherapy ingredients may theoretically reduce fat, these effects have not been supported in peer-reviewed studies. An increasing number of reports demonstrate that subcutaneous injections of a formula containing phosphatidylcholine combined with its emulsifier, deoxycholate, are effective in removing small collections of adipose tissue. Cell lysis, resulting from the detergent action of deoxycholate, may account for this clinical effect. CONCLUSIONS: Mesotherapy is distinct from a method of treating adipose tissue with subcutaneous injections of deoxycholate alone or in combination with phosphatidylcholine. Additional clinical and experimental studies are necessary to more definitively establish the safety and efficacy of these treatments.

Dermatol Surg. 2004 Jul;30(7):1001-8. Related Articles, Links


Detergent effects of sodium deoxycholate are a major feature of an injectable phosphatidylcholine formulation used for localized fat dissolution.

Rotunda AM, Suzuki H, Moy RL, Kolodney MS.

Division of Dermatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA.

BACKGROUND: Phosphatidylcholine injections are becoming an increasingly popular technique to treat localized fat accumulation. This formula is composed primarily of phosphatidylcholine and sodium deoxycholate, a bile salt used to solubilize the natural phospholipid in water. The mechanism through which this injectable phosphatidylcholine formulation causes localized fat reduction is unknown. OBJECTIVE: To investigate the active component and mechanism of action of an injectable phosphatidylcholine formulation in clinical use. METHODS: Cell viability and cell membrane lysis assays were performed on cell cultures and porcine skin after treatment with the phosphatidylcholine formula, isolated sodium deoxycholate, or common laboratory detergents Triton-X 100 and Empigen BB. In addition, we described the histologic changes after injection of these substances into porcine tissue. RESULTS: A significant and comparable loss of cell viability, cell membrane lysis, and disruption of fat and muscle architecture was seen in cell cultures and tissue specimens treated with the phosphatidylcholine formula and isolated sodium deoxycholate. These findings were similar to the effects produced after treatment with laboratory detergents. CONCLUSIONS: The phosphatidylcholine formula popularly used in subcutaneous injections for fat dissolution works primarily as a detergent causing nonspecific lysis of cell membranes. Our findings suggest that sodium deoxycholate is the major active component responsible for cell lysis. Detergent substances may have a role in eliminating unwanted adipose tissue. It is advised that physicians use caution until adequate safety data are available.
 
its a relatively newer treatment, it does work but there are some concerns about its safety.

basically its injecting detergent into fat pockets to break down the cells, which die.
 
Gymgurl said:
Had it done...no difference and it hurt like a son of a bitch
Click to expand...


this is also an issue. the research on its effectiveness in "general" use is a bit lacking. for lipomas where higher doses and concentrations can be used, there does seem to be some validity
 
Mesotherapy has been used in third world countries as an alternative to liposuction and other expensive fat reduction procedures. Mesotherapy clinics have spread up everywhere in those countries, nevertheless I've heard mixed reviews about it. During my stay in Mexico for instance, mesotherapy was advertised as the cure for obesity without the rebound effect, also was advertised as an alternative for local or spot fat reduction (something like the lipo sculpture) and so on. In some cases they even claim to cure some deseases such as baldness, diabetes, and to dramatically improve inmune system for AIDS patients.
Well, just so u know, during my stay in Mexico I worked as a trial attorney for 8 years, and the list of complaints against this mesotherapic clinics was huge. In many cases, the treatment applied required the patient to stop traditional drug treatment and in many cases the results were irreverisble and lethal. YES!!! many people died.

Regarding fat loss, I can attest that many close relatives gave mesotherapy a shot, and although they did drop some weight off in no time, I believe it was mostly water and after discontinuing treatment the weight came back on and then some. They also reported that they felt a lack of energy and kinda depressed at times.
Long story short, mesotherapy is a scamm at least in my book...This is just what I've seen and off course You guys need to be smart enough to decide for yourself and make the right call.

Off course the mesotherapy clinics are still making huge profits at least in Mexico, because they are not regulated by the Secretary of Health, they pay top taxes, and unfortunately is very difficult to make them accountable because they make their customers to sign a waiver of liability, and they are not due to keep medical records (nice huh). Many mesotherapists in Mexico claim to be Doctors even though they don't have a license to practice medicine. ANd it's not like it was just bad luck for going to a bad clinic.


Good luck!
 
A friend of mine does this....orders the stuff for the injections...let me tell you...it is not regulated and she uses what ever she can find and play around with it.....
 
Gymgurl said:
A friend of mine does this....orders the stuff for the injections...let me tell you...it is not regulated and she uses what ever she can find and play around with it.....
Click to expand...
are you sure, meso for fat loss involves 100's on needles
 
NYBodyguard said:
are you sure, meso for fat loss involves 100's on needles
Click to expand...


deoxycholate based (and just lecithin based- worthless) formulas are widely available on the net.

though again dont reccomend this treatment, except perhaps in cases of lipoma
 
Re: mesotherapy - Doesn't work for everyone.

After $2000 spent over 5 months, I had NO FAT LOSS around my waist! I made sure not to change the diet or workouts during that period, just to see. My doctor said that this happens to 10-15% of patients and no one knows why at this point. He is a top plastic surgeon and has treated 1000's of patients, mostly women. In these cases he offers 100% credit towards liposuction therapy, which is cool, but another $5,500....
 
I did this, three treatments, with a hyped up version that had a high deoxy content. I got a minimal results, and a lot of pain and swelling. I also got a stalph infection, two of the times I used it, I can't be possative it was that, But evidence would suggest, it was the culprit. the last one was 3 days in the hospital with iv antibiodics, it was about a week after doing 70 injections in my love handle area. So be carefull.
 
when meso works, it works well, but i have never heard of a guy having good results. Men and women store fat in different ways, male fat is more fibrous than womens iirc that is why men don't get cottage cheese clumps.
 
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