M
MarkusReinhardt
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What to choose from? or are they both just scams.
Birduvsc said:OK, well first of all Mag-10 is not even available to the public yet. I have tried 1-AD and it is a very good supplement. If Mag-10 has what 1-AD has in it.....
Par Deus said:
It does not. Mag-10 has 1-AD's conversion product (17beta-hydroxy-5alpha-androst-1-en-3-one aka 1-testosterone), which is not orally active, thus they have added the ethylcarbonate ester, which I have seen no data on. PA, are you aware of any??
If it does work as well as they claim, the invention of the ester will be something better than the pharmaceutical industry was ever able to come up with, which should make a person a bit sceptical.
Of course, they did get 99% absorption with a flavone
ParDeus
Big Motherfucker bodybuilding magazine
Issue #3 now on-line.
http://www.avantlabs.com/issue3/big_mfr_issue_3.htm
pa1ad said:
I have come to the conclusion that the ethylcarbonate thing was a complete scam. But I do not know who the source of the scam is. Did Bill Roberts scam Tim Patterson into thinking it did something, or did Tim Patterson take the theory from Bill and make up the outrageous claims about it?
Par Deus said:
I do not know what to think.
On one hand, the existing data on oral esters that I am aware of is terrible. I have seen as low as .36% bioavailability with nandrolone undecanoate, I think the highest I have seen is in the 3% range.
So, it seems unlikely that this one would be so much better (and with the cost of 1-test, it certainly needs to be. ) -- particularly considering the pharmaceutical industry uses injections and transdermals because they cannot get a non-C-17AA oral to work.
I found one thing on an ethylcarbonate ester in prednisolone, but it already gets like 70% oral bioavailability without it, so it is hard to consider that as relevant data.
On the other hand, if it doesn't work, this product is going to do NOTHING. With the claims they have made, I have to think they would be done.
It is not like a protein powder, where you could blaim someone for not working hard enough or something. This is an androgen, and everyone knows you can grow on androgens without lifting or eating
I get the feeling that this is their HMB, and that they are willing to lose their current base and take on a whole new following of suckers.
Or maybe they are just going to secretly alpha akylate it
ParDeus
Big Motherfucker bodybuilding magazine
Issue #3 now on-line.
http://www.avantlabs.com/issue3/big_mfr_issue_3.htm
Fortes said:I went to Syntrax's website and read their article "The Making of Orally Active Steroids." I took Chemistry in highschool, but I got a B and I slept through most of it so I know I can't really hang with super-genius steroid chemists like Pat. However, I read the Syntrax THP ether idea and it sounded very compelling. The guy who wrote it mentioned an Ether based steroid called Mepistanolone (developed by some Japanese pharmaceutical co.) or something and stated that the reason a steroidal ether would work is because it is SUPERLIPOPHILIC, meaning it clings to nonpolar solvents within the body, and would/could be absorbed completely by the Lymphatic system, hence bypassing the liver, because of its affinity for the largely lipid based lymphatic system.
Maybe I just completely butchered that article, but that's what I remembered, and it sounded very professional, scientific and compelling all at the same time. Sound like a scam to you, Pat? Because to me it sounds pretty damn good. This syntrax guy can't just go on mentioning that effective, steroidal ether technology was developed by some japanese pharmaceutical company if it wasn't true - if he did, he might as well have flushed his whole companies reputation down the toilet!
Man, if Biotest really is scamming people with Mag-10, they are going to get their reputation royally FUCKED! I feel sorry for them . . . ever since poliquin left, it seems like the website has become a big marketing front. I know these guys have to make money, but do they really have to hype their supps so much? I do frequent T-mag, but I generally stick to their archives section.
pa1ad said:
In fact, one study found the oral administration of testosterone undecanoate led only to an absolute testosterone bioavailability of 6.83 +/- 3.32%. That is very slight, especially considering the fact that in the same study they found the bioavailability of straight testosterone to be 3.56 +/- 2.45% (Eur J Drug Metab Pharmacokinet 1986 Apr-Jun;11(2):145-9). That means TU is just a little less than twice as orally active as free testosterone, which is unimpressive to say the least.
notpuff said:hey par is avant labs planing on making other experimental hormones like 1-test into transdermal?
Fortes said:
Oh yeah, Pat, what about your substrate series? Do you think you made a worthwhile venture with that absorbtion enhancement technology? And can it be coupled with 1-AD? Or would that just be a waste?
I'm still super-curious as to the conversion rate of 1-AD upon its entrance into the liver. Do ever plan on doing a study to determine what it is?
And one last thing: What university are you at, and what is your major? My guess is chemical engineering as for your major . . . with a self-granted emphasis on steroids! A very intriguing major, indeed, at least to any musclehead with half a brain.![]()
Par Deus said:
Yes, we have a 1-test/4-AD combination topical that is being beta tested right now.
ParDeus
Big Mf'r #4 -- Dec. 7th
www.avantlabs.com
notpuff said:In a previous post PA said he knew of a few compounds that were allot more anabolic then test but were never released into the market , any chance avantlabs will make any of these compounds into transdermals?
notpuff said:whats the diffrence between beta version ??
Par Deus said:
PA is so far ahead of me in looking into the existence of such things that I would never catch up, so if we ever do, it is highly unlikely that we would be the first.
notpuff said:
why dont u ask him what he has found?
Par Deus said:
Even if he did know some that would be legal, why in the world would he want to tell me??
notpuff said:Is that why ergopharm isnt putting out a 1-test product?
40butpumpin said:Definitely not scams. I say Mag-10. I've tried both and I give the slight advantage to Mag-10 because I crashed pretty hard on the 1-AD. But it's still a great product nonetheless.
mvmaxx said:It would be interesting to me to see if the 10 people who voted that they are both scams HAVE EVEN TRIED THEM?
Why is it that the people who vote towards negativity have often not even tried the product?
Anyway, 1-AD worked great for me: 18 pounds in 5 weeks and bp went from 285 to 315 4x. I gained an inch on both arms and legs.
My workout partner (Mr Skeptical) also took 1-AD and experienced increase muscle mass and strength. This comes from the same person who never got ANYWHERE from andro.
Another thing I noticed was the joint relief while on 1-AD. Although I did seem to have a lower libido while on it. I'd stack andro with it if I was doing it again (going with real stuff next time).![]()
Me too. I'm trying to compare the cost effectiveness of 1-AD vs 1-test. Assuming the oral availability is about the same for both, the answer would lie in 1-AD's conversion rate. Anyone know what that is???Fortes said:...I'm still super-curious as to the conversion rate of 1-AD upon its entrance into the liver...
Complete Muscle said:Me too. I'm trying to compare the cost effectiveness of 1-AD vs 1-test. Assuming the oral availability is about the same for both, the answer would lie in 1-AD's conversion rate. Anyone know what that is???
Par Deus said:
There is no direct data. The conversion rate of 4-AD (can't recall what tissue) was found to be 15%, and they use the same enzyme.
pa1ad said:
Maybe we have some stupid sense of integrity. I blame my father, that bleeding heart Jimmy Carter like son of a bitch
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