Leydig Cells slowly wearing out

[twistedneck]

Its well known that in elderly men the response of the leydig cells to LH is decreased. As HCG only makes this condition worse is there anything we can do to get them going FULL SPEED again after a cycle?

What if were doing cycles and coming off with Nolvadex to increase the LH ouptut but the testies will not respond as strongly and our test is lower for good, is it TRT time?

Proviron or Masteron?

TW

 

[buckwheat1]

If you use HCG properly then I don't see how it could worsen the leydig's cells response to LH. If you inject small amounts 200-500IU every couple of days through your cycle it would probably keep the boys in shape. The harm comes in when excessive HCG is administeredfor too long of a period of time. I have never read anything that suggests that the larger doses that are done at the end of a cycle cause any issues. I could be wrong. Personally I would go with frequent small injections and never let the boys get to a point where large injections are needed to bring them back to life.

 

[juicin'since17]

500iu or 5000iu you mean? i always took min of 3000iu a week for 3-4 weeks. this steroid manual i got says most guys shoot 5000iu every 5 days. i think 3000iu a week is the starting dose guys

 

[Nelson Montana]

500iu or 5000iu you mean? i always took min of 3000iu a week for 3-4 weeks. this steroid manual i got says most guys shoot 5000iu every 5 days. i think 3000iu a week is the starting dose guys

This is exactly what causes densensitization o the Ledig cells. You're following advice geared to professional competitors. Another example of outrageous excess. (So what else is new?)

I'm on hrt and twice a year I do a course of HCG. Two 500IU shots a day for 3-4 days and that's it. Balls come back and lasts about 2 weeks before I need to go back on hrt.

 

[buckwheat1]

I meant 500IU. Why not take 1-2 shots of low dose HCG and never get to the point where you have atrophy. In the end I don't think that use up more HCG and its not that expensive anyways.

Also, the added test produced naturally can offset sexual side affects that may result from doing a cycle where test is not included. A friend just recently did 5 weeks of Deca by itself. In week 3 he said that he felt his libido drop. He started 500IU every two days. After 5 days he said his libido was back to normal.

If you don't do HCG through out your cycle then I am not sure if large doses are needed if significant atrophy has occurred.

 

[twistedneck]

Is there a way to increase the Leydig cells sensitivity back to youthfull levels? I am thinking about herbal remedy or possibly proviron.

Regarding HCG as a sub for test. According to one doc (Swale) Men just don't 'feel' as good when HCG alone does the job of raising T to high normal. When he titrates his patients using test cyp to the same exact high normal T levels they feel much better sense of well being.. This may have to do with bio available T vs. bound or free T... hmmm

TW

 

[juicin'since17]

hcg longer then 4 weeks is bad ( supposedly) because its bad( dont feel like explaining) i always had the 10,000iu profasi bottle- which diluted with 10cc so i would just fill the syringe up( 3cc) once a week. then theres a 1000iu leftover so ill shoot that sometime in there as well. once hcg is mixed its good for a month , so this worked out nice. dudes with 5000iu amps are forced to use the whole thing at once i guess. ive never had sexual side effects even though i used to subscibe to the " syringe full of testo a week" for years. then again , i always used plenty of hcg

 

[Dr. JK]

Clomid stimulates both LH & FSH. I would try Clomid for 2-4 weeks at 50-100mg ED

 

[geoboy]

This is exactly what causes densensitization o the Ledig cells. You're following advice geared to professional competitors. Another example of outrageous excess. (So what else is new?)

I'm on hrt and twice a year I do a course of HCG. Two 500IU shots a day for 3-4 days and that's it. Balls come back and lasts about 2 weeks before I need to go back on hrt.

doing it your way (five hundred iu twice a day) for 4 days, is there any estrogen issue to deal with?

also, would this dose be effective for recovery as well as maintenence?

 

[Johnny Gringo]

Bump...I'm very interested in the Leydig cells aspect of this.

 

[geoboy]

doing it your way (five hundred iu twice a day) for 4 days, is there any estrogen issue to deal with?

also, would this dose be effective for recovery as well as maintenence?

bumpterbation

 

[Triple J]

gh is a good rejuvanator and some reports testify that it helps restore balls and cock

 

[gretak911]

I think that the best way to cycle and keep your balls in shape is to take hcg during the entire cycle at 500iu's every 4 or 5 days. The only negative result that I can forsee with this method is that I'm not sure how much HCG it takes to create LH desensitization so that when you stop your cycle and hit the comid maybe you'll need longer to recover. Also there is the increase in estrogen as a result of the HCG but usually your anti-E will take care of this.
As to the original question: I don't know of any supplements that can regenerate leydig cell response.

 

[sh4dowf4lcon]

doing it your way (five hundred iu twice a day) for 4 days, is there any estrogen issue to deal with?

also, would this dose be effective for recovery as well as maintenence?

Since Nelson has not answered I will answer and I am sure he will correct if needed. If you are referring to excessive estrogen or gyno sides from HCG, the answer is no. 500-1000 iu for 3-4 days is enough to take care of testicular maintenence (in most) without causing estrogen related sides or desensitization.

When I used hcg I did 500iu 2 times a day for 4-5 days toward the end of my last cycle and I never had gyno issues or estrogen related sides.
Guys at my gym run 12-16 week cycles, and they use hcg @ the 8wk mark for seven days @ 1000iu a day(2shots), and then again the last week of their cycles @ 1000iu daily (2 shots) for 7-9 days. They look good and report no sides. Just healthy balls.

 

[Nelson Montana]

I think aromatization caused by HCG is overstated.

HCG should not be used for "maintenence." It will lose its effectiveness if overused.

 

[OXANDRIN]

I think aromatization caused by HCG is overstated.

HCG should not be used for "maintenence." It will lose its effectiveness if overused.

is that because HCG mimics LH?

 

[Mini Viper]

as posted by OXANDRIN

is that because HCG mimics LH?

Yes, the activity of HCG in the male body is due to its ability to mimic LH (luteinizing hormone), a pituitary hormone that stimulates Leydig's cells in the testes to manufacture testosterone.
The stimulation of HCG causes the testicles to rapidly return to their normal size and level of activity.
The duration use of HCG should be no longer than 2-3 weeks because the drug can function to desensitize the Leydig's cells to LH, thus hindering return to homeostasis. Dosages of HCG use is exactly as Nelson mentioned above!

Mini

 

[geoboy]

thanks guys.

what is the comparable dose if using the synthetic hcg (pregnyl) to the 500iu hcg?

 

[Ashamed]

thanks guys.

what is the comparable dose if using the synthetic hcg (pregnyl) to the 500iu hcg?

same 500-1000iu