Lets re-cap what esters are and what they accomplish

[Andy13]

I don't doubt that the ester patents claim "higher mg/mL obtained with ester" and "reduced injection pain with ester."

But let us not confuse patents with peer reviewed scintific journals. Patents are written in a highly inclusive format with statements made regardless of experimental basis. This is to protect the invention from taken, scewed slightly, and then re-submitted by another party.

Hydrolysis of the ester occurs and the interphase. And ester length does indeed increase oil solubility of the steroid.. it is for this reason that molecules with longer esters give rise to hormone levels that don't peak as high as short esters and don't return to baseline as fast either.

In other words, I think the pharmacological evolutionary persistance of acetate, prop, enanthate, etc esters is rooted deeper than simple administration vehicle value.

 

[Animal]

And your point is what?

I'm explaining the succession of how the usage went from creation of esters to use by the medical community.

The MEDICAL community took the esters and WITHOUT any research concluded INCORRECTLY as do many of you, that longer esters are better.

Cyclic esters are worse, ie, the Np vs Npp study wherein the abstract they discuss how it's well know by the med community that cyclic esters don't have the properties they should for their long ester.

On michael Mooney's site is the ester release rate for a long and short ester.

I have the study on the re-uptake as well as the study on depot location, ester length, and bioavailibility.

The insuation appears to be that I'm making all this up from a patent intro that I've read while the fact is I've read the MEDICAL research on the subject quite extensively which the PRACTIONERS are ignoring.

 

[Animal]

And a cricket says:

'CHIRP!'

 

[instynct999]

and of course there is some consideration to overall depot size, the type of oil/solvents used, and the site injected which all play a role in depot mechanics and rate of release

 

[Animal]

A study was done with 100mg total hormone injected into same location bilaterally.

In one it was 100mg in 1ml depot.

In the other it was 100mg/ml in a 4ml depot or 25mg/ml.

Guess what the results were?

 

[Triple J]

The 100mg/ml released faster than the 25mg/ml

 

[Animal]

HAHA!

 

[bicepts101]

i wanna hear more on this