well i started it to prevent gyno. I didnt even get bloat yet but decided to take it before i get any so i popped 12.5 and it had a very negative effect on my libido....couldnt keep it up. That was the only change made to my regiment so I thought it must have killed all my estrogen. So i pulled it down to 6.25 mon/thurs and if I need to i will bump it up.