Absolutely a no-no. Have you read that they are beginning to use Topiramate for bi-polar disorder? There are definitely no weight gain issues with Topiramate, in fact, she's almost guaranteed to LOSE weight on it, they are researching it to release it as a weight loss drug now. This is off your question, but I believe she needs some type of treatment for her disorder. I read your post, and your relationship is not in a good place....and it will only elevate into resentment for each other - and your right, your going to feed off of each others "attitude". You can't go on without a remedy in mind, and right now you don't have one. Have her talk to her doc about the Topiramate, or at least do some reading about it. How great would it be to have her mood stabilized, and lose weight too???