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dallascowboys25
New member
hey what's up all I just started my first cycle 6 days ago and like my second day in l started felling like shit. I have read about test flue and was just wondering when that shit goes away and you start felling good.
just started my first cycle and fell like shit
- Thread starter dallascowboys25
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dallascowboys25
New member
600mg primo and 250 mg test-e a week. I forgot to post that my bad
dallascowboys25
New member
man this sucks how long does it last
needtogetaas
New member
A week tops man
zsimpson22
New member
Had the same shit man. Mine lasted about 5 days. I was very tired feeling and lethargic. Shit should be gone anyday now bro. Shouldn't last past tomorrow or next day
dallascowboys25
New member
yea I deff fell better today than I did 2 days ago. That's good to hear
you will be fine bro, just push through it... a week at the very most but I think you will get better sooner and then you will be on top of the world bro! just push through...
That is a pretty low dose of test to be getting that side effect IMO, but regardless it should pass soon.
stolen but easier than typing it out--test flu is a natural defense mechanism - to the sudden increase in exogenous hormone levels. Its the body's way of trying to "flush" out the foreign entity it perceives is there (just as it does w/ a flu virus). There has also been some connection between high BA content and immune response. think the combination of sudden increased hormone levels and a foreign substance being injected into the muscle can cause these symptoms. Some people are sensitive, some arent. Certain people don’t experience it at all and some might just get mild chills (low grade fever) or a runny nose for a few days and not even take much note of it.
etiocholanolone represents only about 20% of the metabolites of testosterone in people. Maybe folks who experience this reaction to testosteone have particularly high levels of 17 beta hydroxysteroid dehydrogenase, the enzyme that converts testosterone into etiocholanolone. Or an isoform of the enzyme that makes the conversion more efficient.
Etiocholanolone is believed to produce fever and flu-like aches and pains because it induces the systemic release of Interleukin-1, a powerful proinflammatory cytokine.
Etiocholanolone is the 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine and is androgenically inactive. Classified a ketosteroid, it causes fever (it is a pyrogen), immunostimulation and leukocytosis. The pyrogenic effect of Etiocholanolone has been shown to be due to the release of interleukin-1 (IL-1) from the leukocytes that are mobilized in response to its production or injection. Etiocholanolone has anticonvulsant activity and may be an endogenous modulator of seizure susceptibility. Significantly increased values of etiocholanolone (along with testoterone and androsterone) an be detected in the urine of men with androgenic alopecia (male pattern baldness).
http://www.hmdb.ca/metabolites/HMDB00490
etiocholanolone represents only about 20% of the metabolites of testosterone in people. Maybe folks who experience this reaction to testosteone have particularly high levels of 17 beta hydroxysteroid dehydrogenase, the enzyme that converts testosterone into etiocholanolone. Or an isoform of the enzyme that makes the conversion more efficient.
Etiocholanolone is believed to produce fever and flu-like aches and pains because it induces the systemic release of Interleukin-1, a powerful proinflammatory cytokine.
Etiocholanolone is the 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine and is androgenically inactive. Classified a ketosteroid, it causes fever (it is a pyrogen), immunostimulation and leukocytosis. The pyrogenic effect of Etiocholanolone has been shown to be due to the release of interleukin-1 (IL-1) from the leukocytes that are mobilized in response to its production or injection. Etiocholanolone has anticonvulsant activity and may be an endogenous modulator of seizure susceptibility. Significantly increased values of etiocholanolone (along with testoterone and androsterone) an be detected in the urine of men with androgenic alopecia (male pattern baldness).
http://www.hmdb.ca/metabolites/HMDB00490
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