Juice loosing its effectiveness?

[bigrand]

I just finished a long bulker/cutter and want to jump on again in a few weeks (cycle didnt go the way i wanted it to).......
people say AAS loose its effectiveness because of receptor burnout. What aobut those AAS that dont have much interaction with the AR, like Deca and anadrol which are both much more anabolic than androgenic? Does your body "down regulate" to increased nitrogen retention and increased hematopoesis like it would with the AR? Ive noticed that those type of drugs tend to work longer for me and recovery seems to be easier (highly androgenic drugs really shut you down). Also, the lack of estrogen keeps me from shutting down hard. From what ive read, progesterone plays a role in this and gyno, but its an additory factor and Estrogen is the neccessary factor.

Thoughts?

 

[scout69]

I've heard the same shit, but it all depends on you, It's not the smartest thing to do to go from one cycle to another but I've done it several times and I have no complaints

 

[bigrand]

Well, i figure if i can gut my nuts back to normal, im at least partially recovered. Keeping the HPTA suppressed completly for a long time makes it harder to recover when done, but im guessing if you at least jump start it a little, it keeps you from being complelty supressed for the duration of both cycles. A short break w/ some recovery between cycles is better than none!

 

[digimon7068]

I just finished a long bulker/cutter and want to jump on again in a few weeks (cycle didnt go the way i wanted it to).......
people say AAS loose its effectiveness because of receptor burnout. What aobut those AAS that dont have much interaction with the AR, like Deca and anadrol which are both much more anabolic than androgenic? Does your body "down regulate" to increased nitrogen retention and increased hematopoesis like it would with the AR? Ive noticed that those type of drugs tend to work longer for me and recovery seems to be easier (highly androgenic drugs really shut you down). Also, the lack of estrogen keeps me from shutting down hard. From what ive read, progesterone plays a role in this and gyno, but its an additory factor and Estrogen is the neccessary factor.

Thoughts?

Anadrol is the most androgenic of all steroids.

 

[gymratforlife]

Anadrol is the most androgenic of all steroids.

lol I thought the same thing

 

[bigrand]

Anadrol does NOT bind to the AR receptor well, its a class II, anabolism is through non AR mediated pathways. Its not highly androgenic. Its highly anabolic.

 

[Bulldog_10]

I'd give your body a rest bro. Play it safe and just learn from this cycle, and apply what you learned to making your next one better. No one likes coming off, especially when you didn't meet your goals from the cycle...but in the long term, you're better off doing what you planned on and stopping for a little bit to let your body recover.

 

[bigrand]

Thanx bulldog, im just wondering how long i should take off. Im getting so close to achieveing what i started 5 years ago (was 250lbs at 6 feet without working out, all fat) and i wanted to get to showing abs at 225 by summer! After that, i could take some time off! i think its cuz my cutting with drol has gone so good, i wanted to do a short NPP drol cycle followed by a short cutter with drol again and i feel id be right there now that i have my diet and training the best ive had it ever.

Im currently 1 week into recovery, so ill give it a little time and see how i feel.

 

[ksbst9mm]

I'd give your body a rest bro. Play it safe and just learn from this cycle, and apply what you learned to making your next one better. No one likes coming off, especially when you didn't meet your goals from the cycle...but in the long term, you're better off doing what you planned on and stopping for a little bit to let your body recover.

could have not been said better!! props bro.

ksbst9mm

 

[digimon7068]

Anadrol does NOT bind to the AR receptor well, its a class II, anabolism is through non AR mediated pathways. Its not highly androgenic. Its highly anabolic.

Hmmm, I was under the impression that "androgenic" referred to the masculinization characteristics of a particular compound and I made my comment based upon that understanding. So, I'm wrong?

 

[bigrand]

Androgenic characteristics occur through the androgen receptor. Other effects (nitro retntion, creatine synth, ect) are AR independent and anabolic moreso than androgenic. Things like test and tren bind heavily to the AR and give the most androgenic effects. Anadrols main effects come through increased RBC production, fluid/glycogen retention intermuscularly, incresed nitro retention.