Not a miracle cure, but it really helps my L elbow. I had chronic pain due to surgical removal of the fascia covering the bones. Just scin rubbing on bone. The slightest jolt and it would hurt for weeks. I never could do heavy bench because of pain. Blah, Blah, Blah........To make this story short, I use Glucoseamine Sulfate/Condroitin combo at 2500mg each. Like WD40 for your joints. GREAT STUFF! I think long term, it'll actually change degeneration for the better.
Glucosamine, most commonly known in the form glucosamine sulfate, is a simple molecule derived from glucose, the principal sugar found in blood, and glutamine, a dietary nonessential amino acid.
In glucosamine, one oxygen atom in glucose is replaced by a nitrogen atom. The chemical term for this modified form of glucose is amino sugar.
Glucosamine is produced naturally in the body, where it is a key building block for making cartilage. In Europe, glucosamine is widely used to treat osteoarthritis. Studies show that glucosamine supplements relieve pain and other arthritis symptoms. Interestingly, these improvements seem to last for weeks after glucosamine supplements are discontinued.
This observation has led to the led to the exciting idea that glucosamine may actually make a deep change in osteoarthritis, rather than simply relieving symptoms. Conventional treatments for arthritis reduce the symptoms but do not slow the actual progress of the disease: in fact; nonsteriodal anti-inflammoratory drugs, such as, indomethacin, may actually speed the progression of osteoarthritis by interfering with cartilage repair amd promoting cartilage destruction.
In contrast, glucosamine appears to go beyond treating the symptoms to actually slowing the disease itself.
Chondroitin sulfate belongs to a class of biological compounds known as glycosaminoglycans. These long, unbranched carbohydrates are essential building blocks of the connective tissue matrix, cartilage, and synovial fluid.
Dietary supplementation with glycosaminoglycans, such as chondroitin sulfate (possibly in combination with glucosamine), has been suggested to stimulate cartilage matrix synthesis, inhibit cartilage degrading enzymes, and help to prevent thrombus, plaque and fibrin formation in synovial and subchondral blood vessels.
Based on the evidence of preliminary double-blind studies, chrondroitin is widely used in Europe as a treatment for osteoarthritis, a condition that increases in frequency with age.
There is some data to suggest that chondroitin (possibly in combination with glucosamine) may offer protection against inflammatory joint disease in addition to the treatment of such conditions. Current drug treatments for osteoarthritis, such as NSAIDs, (nonsteroidal anti-imflammatory drugs), can provide effective symptomatic relief; however, they may not actually slow down disease progression. Some anti-inflammatory drugs may actually aggravate the underlying disease process.