I just came across a message

[Kodesh]

on steroids.ru, and it basically said that it is possible to get gyno from using nolvadex by itself...anyone knows anything about it? That could explain why some people are getting gyno after their cycles are done...

 

[DrJMW]

Antiestrogens

Of all the antiestrogens, nolva is the worst. It blocks all receptors; it does not prevent the formation of estrogen. The liver and kidneys now have to get rid of all that estrogen floating around in the blood. Now, you get some rebound from the estrogen that has pooled. In people who are endomorphs--obese tendencies--this is seen pretty readily. Arimidex is best for these folks. Clomid is good during and post-cycle for mesomorphs and ectomorphs. As a matter of fact, arimidex and clomid are the only antiestrogens I use with my clients now. Arimidex inhibits the formation of estrogen, and clomid selectively blocks estrogen receptors (breast tissue, adipose).

 

[eric123]

In order to effectifely use Clomid as an anti-estrogen, how much would you advise and when? If one were on a cycle of d-bol, test, and EQ, when would that person start using clomid to prevent gyno?

 

[Julez]

I suppose it could be possible. The body requies a balance of both estrogen and testosterone (at different ratios in men and women). As DrJMW states, Nolvadex blocks all estogens receptors. It is possible that this could cause a negative feedback on the hyperthamlamus as the body believes there is a deficit of estrogen. Therefore, the body tries to reach homeostasis by attempting to create more estogen (I think by the same process as test - LH and/or FSH - anyone enlighten me?). That would mean that on stopping Nolvadex and unblocking all these receptors, it would be like opening floodgate.

Just my explanation of how, theoritically, this could be possible.