simple
I'm thinking people aren't replying because this is a real simple question. First, DMSO is transdermal itself. So, I would assume that you would measure the proper amount of a certain substance, say Yohimbine. Then also measure an amount of DMSO, whatever ratio of DMSO to Yohimbine will be the concentration of your new transdermal. You have to make sure that the concentration isn't too high or it won't be effective. And I think thats about it....I've never done it, but thats just coming from my basic chemistry knowledge. I may be wrong, but I think its pretty simple, so long as you're not using a substance with too large of a molecule.