how much HGH to take & for how long?

[lil_tex]

I'm starting a 12 week cycle of sus 500mg a week I was thinking about using HGH this would be my first time(using HGH). I can only afford one kit right now (100 IU) is it worth doing if I can't do it longer? And how much should I take? I hear that everyone takes about 3-6 iu's a day. So any advice on dosage and if it's worth it would be appreciated.... I am 6ft 230lbs 14% bf
Thanks

 

[showtime2004]

I'm starting a 12 week cycle of sus 500mg a week I was thinking about using HGH this would be my first time(using HGH). I can only afford one kit right now (100 IU) is it worth doing if I can't do it longer? And how much should I take? I hear that everyone takes about 3-6 iu's a day. So any advice on dosage and if it's worth it would be appreciated.... I am 6ft 230lbs 14% bf
Thanks

how old are you?

 

[HeadHoncho]

Do not bother to do only 100iu.

 

[lil_tex]

how old are you?

Sorry I'm 29 going on 30 here in a few months

 

[Macronne]

If you can afford HGH for about 6 months, then dont do it. Start with 2-3 iu first week then go up to 6-8 iu.

Is this your first cycle??

 

[bigpat]

i suggest 2ui per day for more then 3 month
5day on/ 2day off
basic line !!!

 

[VictorBR]

2-4 iu ed for at least 3-4 months would give good results , no need to go that high to see results ..


Victor

 

[locrian]

2iu's 4x a week for 12.5 weeks would work

 

[lil_tex]

 

[lil_tex]

If you can afford HGH for about 6 months, then dont do it. Start with 2-3 iu first week then go up to 6-8 iu.

Is this your first cycle??

This will be the first time I use HGH but I have juiced before.....

 

[locrian]

hey bigpat.... that babe in your vatar is makin me drool...... damn

 

[lil_tex]

2-4 iu ed for at least 3-4 months would give good results , no need to go that high to see results ..


Victor

Well I went ahead and got 1 100IU kit and hopefully by the time I'm done with it I can afford another one. Thanks for the advice guys...

 

[will b huge]

Well I went ahead and got 1 100IU kit and hopefully by the time I'm done with it I can afford another one. Thanks for the advice guys...

100iu wont do it bro......

You should go for a solid 6 months of at least 2iu/day for the first month or two, then 3iu for awhile, and not a big reason for you to ever go higher than 4iu/day......

Some go ED, some go 5on/2off....some go EOD, a few go 6on/1off......

 

[ItalianMuscle27]

100iu wont do it bro......

You should go for a solid 6 months of at least 2iu/day for the first month or two, then 3iu for awhile, and not a big reason for you to ever go higher than 4iu/day......

Some go ED, some go 5on/2off....some go EOD, a few go 6on/1off......

Excellent advice! Couldnt have said it better myself.

 

[Ulter]

2iu/day is practically useless at 29 yrs old. I don't care how long you take it for.
Even at 4iu/day it will not yield much if any growth but at least will some positive affect on fat loss.
You had it right in the first place. You don't have enough.

 

[will b huge]

2iu/day is practically useless at 29 yrs old. I don't care how long you take it for.
Even at 4iu/day it will not yield much if any growth but at least will some positive affect on fat loss.
You had it right in the first place. You don't have enough.

Ulter, in your humble expert opinion----do you recommend breaking up the 4iu/day into 2 injects (like one at 5-8am and 2-5pm...)

Also, are you an advocate of ED use???? (im guessing you are)

Then again, if your looking at GH as even at 4iu won't yield much growth; then you are definitely gonna support insulin usage too.......

 

[lrg&inCHARGE]

Ulter, in your humble expert opinion----do you recommend breaking up the 4iu/day into 2 injects (like one at 5-8am and 2-5pm...)

Also, are you an advocate of ED use???? (im guessing you are)

Interested in your opinion on these questions as well

 

[ItalianMuscle27]

2iu/day is practically useless at 29 yrs old. I don't care how long you take it for.
Even at 4iu/day it will not yield much if any growth but at least will some positive affect on fat loss.
You had it right in the first place. You don't have enough.

Dont know where you got that information from, but 2ius yields fantastic results. I use 2ius/day with a 6on/1off cycle. I love the results it adds. My boy uses 2iu/day witha 5on/2off cycle and he is at 4% bodyfat! You must have some poo poo gh if your using 4ius+/day and not getting any growth.. I see an HRT doctor, and he explained everything...Its about keeping your blood level for optimum results. Too much is harmful in long term use..

 

[bigjd69]

You won't really notice anything until after the 3rd month, is when it really started to kick in for me. 2ius 5day 2 off since March

 

[lil_tex]

Dont know where you got that information from, but 2ius yields fantastic results. I use 2ius/day with a 6on/1off cycle. I love the results it adds. My boy uses 2iu/day witha 5on/2off cycle and he is at 4% bodyfat! You must have some poo poo gh if your using 4ius+/day and not getting any growth.. I see an HRT doctor, and he explained everything...Its about keeping your blood level for optimum results. Too much is harmful in long term use..

Do you guys recommend taking it in the morning or night? Right now I’m taking it 2iu every night but I have heard even at that dose some split it into morning and night.
I am also stacking it with Sus 250 500mg a week also.....

 

[Ulter]

Dont know where you got that information from, but 2ius yields fantastic results. I use 2ius/day with a 6on/1off cycle. I love the results it adds. My boy uses 2iu/day witha 5on/2off cycle and he is at 4% bodyfat! You must have some poo poo gh if your using 4ius+/day and not getting any growth.. I see an HRT doctor, and he explained everything...Its about keeping your blood level for optimum results. Too much is harmful in long term use..

I've used Serostim and I get it at Walgreen's so I'm pretty sure it's good.
Where do I get the information? From 20 years of experience and talking to 2 or 3 thousand people using it every year. Last year I answered 16,000 steroids related questions and have so much more practical experience than your HRT doc that it's ridiculous. Even his dosing schedule is wrong.
He told you "it's about keeping your blood levels optimum" did he? Well let him know the rGH doesn't last long enough to develop constant blood levels.

Serostim is dosed as 18iu/day in their kit. So the average GH deficient AIDS person uses EIGHTEEN iu/day. Studies on children with gh deficiencies are done with 6iu/day. In most medical research they use .125 to .250iu/kg per week to replace deficient gh. If you weigh 90kg that's 1.6iu/day to 3.2iu/day. So your 2iu/day would fall right inbetween. So you're taking the amount researchers give someone in order to replace what their body doesn't make by itself.

GH should be used when you get up in the morning.

 

[ItalianMuscle27]

So my doctor with 15yrs+ experience in the field of HRT therapy, & who also works exclusively with pfizer doing research, has no idea what he is talking about eh? Keeping the blood level, is only one area..I dont have the time nor the energy to type all the information out. If you have the the time read the New Engalnd Journal of Medicine on the topic.

www.nejm.org

Or Read JAMA, Nov.13, 2002 vol.288, No.18

I am using the Saizen, more potent than the Serostim. I have used it before, and didnt get nearly the same results as I am with the Saizen! I have never claimed to be an expert, I am just quoting my doctor. If you have 20 years experience and answered 16000+ questions, you must be an expert! Congratulations..

 

[Ulter]

Yes, that's right I am an expert. Now you have a handle on it.

Your endo's background on HRT gives him virtually no experience with a body builder's use of rGH. 2iu/day is great if your old and trying to stay young or if you're deficient. I am sure your doc would prescribe 100mg/test per week too. But that's not really what we're after here is it?

 

[proken]

Timing is key... rhgh is very short lived in the blood stream. I have had excellent results taking 8iu's a day split 4x4. However, I have recently tried "timing" and am getting better results from just two iu's per day. I take the first iu right after working out, the second iu after the largest protien/nutrient meal of the day. It's sort of like being thirsty. You drink water when your body tells you too and I think if the body had a mechanism to tell you when to injest rhgh it would be most needed and felt after a hard work out and after a good protien drink... Just food for thought. Just as a note, when I'm on prop, or do orals, I use the same line of thinking.

 

[ItalianMuscle27]

Expert? Arent we all an expert. Everyone thinks they know everything.. Kinda funny you should mention the fact that my doctor has no experience with bodybuilders. He used to be a bb, but doesnt compete anymore. A few of his clients are also professional body builders. I wish I could mention their names, but I dont even know who they are.. I would take the advice from a doctor, before i would take advice from an invisible face..

 

[will b huge]

Expert? Arent we all an expert. Everyone thinks they know everything.. Kinda funny you should mention the fact that my doctor has no experience with bodybuilders. He used to be a bb, but doesnt compete anymore. A few of his clients are also professional body builders. I wish I could mention their names, but I dont even know who they are.. I would take the advice from a doctor, before i would take advice from an invisible face..

Bro, you should probably shut up while your ahead.....

Also, if your taking advice from your doctor before taking anything from invisible faces (like you state in your thread above)-----THEN WHAT ARE YOU DOING ON HERE???????? (just trying to harass somebody)


CMON NOW BRO---GET YOUR HEAD OUT OF YOUR ASS and Lets all get along---OK????

 

[ed2005]

Cheez let's all lighten up here...No one is throwing stones, just offering opinions. People have different views, that's why we have message boards...Different things work for different people...Hell, life is all about being different......
A few points:
I've had great results on 2ius a day but then I know others who haven't on 10ius....
I thought Saizen was the absolute ticket, the best, but unfortunately over priced and hard to get on the black market, so Jintropin is my poison.
Lil Tex DO NOT use your GH at night! At 29 your own pituitary will be releasing normal amounts of natty GH and you'll be shutting that down. I also have to agree that unless you plan on running for 6 months you are losing out on optimising your investment. You may well see some initial results within the first week but others can take 3 months to strike it lucky..You really should use growth for a few months and then kick in your AAS cycle..
Cheers
Ed

 

[Outtlaw]

Dont know where you got that information from, but 2ius yields fantastic results. I use 2ius/day with a 6on/1off cycle. I love the results it adds. My boy uses 2iu/day witha 5on/2off cycle and he is at 4% bodyfat! You must have some poo poo gh if your using 4ius+/day and not getting any growth.. I see an HRT doctor, and he explained everything...Its about keeping your blood level for optimum results. Too much is harmful in long term use..

You're not gonna get massive by doing 2iu/day of gh. But then there's always the idiot that says they blew up taking 100mg/wk of test.

 

[Outtlaw]

Serostim is dosed as 18iu/day in their kit. So the average GH deficient AIDS person uses EIGHTEEN iu/day. Studies on children with gh deficiencies are done with 6iu/day. In most medical research they use .125 to .250iu/kg per week to replace deficient gh. If you weigh 90kg that's 1.6iu/day to 3.2iu/day. So your 2iu/day would fall right inbetween. So you're taking the amount researchers give someone in order to replace what their body doesn't make by itself.

GH should be used when you get up in the morning.

I wouldnt be so quick to say that HIV/AIDS patients have a gh deficiency, as from what I've read this has not been proven. There is the idea that they can become somewhat resistant, but I wouldnt classify AIDS patients in the same group as gh deficient kids.

 

[mt]

I, too, like using HGH but have to ration it because of the cost. It has been proven that high intensity exercise produces HGH so I keep that in mind when using HGH. About 3 times per week I do a real ball busting high intensity workout and just before that I take a shot of l-tyrosine/alcar/ornithine since that "supposely" is suppose to stimulate HGH production. On the days I don't train this way (4 days/wk) are the times I supplement with HGH (2ius). That way a 100 IU kit will last me just over 3 months. I know it's not ideal and I'd love to take 4ius or even 2ius per day or even 5 days on 2 days off but for a lot of us in real life we have to make due. Even though it's not ideal it's still better than nothing and I believe I'm getting far more HGH going through my body than the average person my age (just over 40 years). I find that in life you rarely get the ideal but have to settle for the best possible situation given the current circumstances.

 

[Outtlaw]

Lil Tex DO NOT use your GH at night! At 29 your own pituitary will be releasing normal amounts of natty GH and you'll be shutting that down. I also have to agree that unless you plan on running for 6 months you are losing out on optimising your investment. You may well see some initial results within the first week but others can take 3 months to strike it lucky..You really should use growth for a few months and then kick in your AAS cycle..
Cheers
Ed

I have yet to see any study proving how long exogenous gh supresses endogenous production of gh. Therefor to say that gh is better taken in the morning simply because it wont surpress your natural gh is not really a viable justification.

 

[mt]

I have yet to see any study proving how long exogenous gh supresses endogenous production of gh. Therefor to say that gh is better taken in the morning simply because it wont surpress your natural gh is not really a viable justification.

Doesn't GH have a relatively short half life?Even an older person produces some at night during the first few hours of sleep. It seems to make intuitive sense that if you take it just before you go to sleep it will suppress your own natural production but if you take right when you wake up in the morning it will be out of your system by the time you go to bed at night so in a sense you'll be getting two shots of HGH instead of just the one at night.

I think the reason it is recommended by the manufactors to take it before you go to sleep is that it is intended for those that don't produce any or not enough of their own and not as an addition to your own production.

 

[Outtlaw]

Doesn't GH have a relatively short half life?Even an older person produces some at night during the first few hours of sleep. It seems to make intuitive sense that if you take it just before you go to sleep it will suppress your own natural production but if you take right when you wake up in the morning it will be out of your system by the time you go to bed at night so in a sense you'll be getting two shots of HGH instead of just the one at night.

I think the reason it is recommended by the manufactors to take it before you go to sleep is that it is intended for those that don't produce any or not enough of their own and not as an addition to your own production.

True, but I've seen things that say gh will supress natural production for up to 24hrs. So until I see a study proving how long the supression last, Im not willing to back peoples claims that say supression last only for a few hrs.

And if supression did last for up to 24hrs, then it wouldnt make a difference if you took it in the AM or not, cause your nightly release of gh would still be supressed.

 

[junk]

I've used Serostim and I get it at Walgreen's so I'm pretty sure it's good.
Where do I get the information? From 20 years of experience and talking to 2 or 3 thousand people using it every year. Last year I answered 16,000 steroids related questions and have so much more practical experience than your HRT doc that it's ridiculous. Even his dosing schedule is wrong.
He told you "it's about keeping your blood levels optimum" did he? Well let him know the rGH doesn't last long enough to develop constant blood levels.

Serostim is dosed as 18iu/day in their kit. So the average GH deficient AIDS person uses EIGHTEEN iu/day. Studies on children with gh deficiencies are done with 6iu/day. In most medical research they use .125 to .250iu/kg per week to replace deficient gh. If you weigh 90kg that's 1.6iu/day to 3.2iu/day. So your 2iu/day would fall right inbetween. So you're taking the amount researchers give someone in order to replace what their body doesn't make by itself.

GH should be used when you get up in the morning.

AMEN AMEN AMEN
Took the words out of my mouth. The benefit for people age 30 who intend to take 2iu ED is mute. Anti aging doctors usually recommend something like 1iu ED. The reason why GH is bashed so much as being useless, is because it is relatively useless for bodybuilders (though some benefits still exist) at dosages of 2iu. I personally go with 15-20IU EOD.

 

[Ulter]

I wouldnt be so quick to say that HIV/AIDS patients have a gh deficiency, as from what I've read this has not been proven. There is the idea that they can become somewhat resistant, but I wouldnt classify AIDS patients in the same group as gh deficient kids.

I wouldn't be so quick to quote me as saying that HIV/AIDS patients have a gh deficiency. Because that's not what my post says. It refers to AIDS patients that DO have a GH deficiency. Which follows the reasoning that this is the approved use for serostim.

 

[Outtlaw]

I wouldn't be so quick to quote me as saying that HIV/AIDS patients have a gh deficiency. Because that's not what my post says. It refers to AIDS patients that DO have a GH deficiency. Which follows the reasoning that this is the approved use for serostim.

OK, maybe I misinterpreted your post. It sounded like you were saying that all aids patients were gh deficient. But gh use is also approved for wasting (maybe not by serostim). And you dont have to have a gh deficiency to have body wasting.

 

[mt]

True, but I've seen things that say gh will supress natural production for up to 24hrs. So until I see a study proving how long the supression last, Im not willing to back peoples claims that say supression last only for a few hrs.

And if supression did last for up to 24hrs, then it wouldnt make a difference if you took it in the AM or not, cause your nightly release of gh would still be supressed.

Well, there have been studies that show a spike in HGH when a certain level of physical exertion is preformed, such as high intensity exercises that also includes things like sprints and the like -- not just weight training. Also, about ten years ago I had to take some kind of insulin test or something where they injected insulin into my veins and then when I was about to pass out (I actually did pass out) they would then inject dextrose into another vein. One of the things that was shown was there was a definite spike in HGH levels when my blood sugar was low. So, assuming I had a good nights sleep, which I did, and produced normal levels of GH (no reason to assume I didn't), then this would prove that a production of HGH eight hours before my test had no "suppressive" effect on my own HGH production. And if a GH surge (such as during sleep) would produce a suppressive effect for 24 hours then it would not be possible to have any other kind of GH spike during the day or during high intensity exercise. Remember, just like testosterone, your body doesn't know where the hormone is coming from. Whether it's from your pituitary or from an insulin pin it's all the same as far as your body is concerned. This was explained to me by my endocrinologist in regard to testosterone and he said that it also applied to HGH.

 

[ed2005]

A gland is a gland and hormones are hormones. A gland will only produce the amount of hormone neccessary to maintain your body, whatever that amount is for that individual. Regardless if it is testosterone or GH or anything else for that matter. Once you supplement your own natural supply the gland will adjust the amount of hormone to cater for the extra uptake in your body, in other words stop producing. The body will always try to achieve an equalibrium and maintain balance. I will research in work tommorow to see if I can come up with some studies for you Outlaw but the theory alone makes perfect sense and besides why would anyone wish to risk their own natural supply, regardless.

 

[Outtlaw]

Well, there have been studies that show a spike in HGH when a certain level of physical exertion is preformed, such as high intensity exercises that also includes things like sprints and the like -- not just weight training. Also, about ten years ago I had to take some kind of insulin test or something where they injected insulin into my veins and then when I was about to pass out (I actually did pass out) they would then inject dextrose into another vein. One of the things that was shown was there was a definite spike in HGH levels when my blood sugar was low. So, assuming I had a good nights sleep, which I did, and produced normal levels of GH (no reason to assume I didn't), then this would prove that a production of HGH eight hours before my test had no "suppressive" effect on my own HGH production. And if a GH surge (such as during sleep) would produce a suppressive effect for 24 hours then it would not be possible to have any other kind of GH spike during the day or during high intensity exercise. Remember, just like testosterone, your body doesn't know where the hormone is coming from. Whether it's from your pituitary or from an insulin pin it's all the same as far as your body is concerned. This was explained to me by my endocrinologist in regard to testosterone and he said that it also applied to HGH.

Problem is the reports I've seen show conflicting information. The one consistent thing is that exo gh is shown to cause supression. For how long is the question. What your natural spikes show dont have a lot of merit for me because normally when people use gh, they're getting a spike much higher than the natural gh spike.

 

[Outtlaw]

I will research in work tommorow to see if I can come up with some studies for you Outlaw but the theory alone makes perfect sense and besides why would anyone wish to risk their own natural supply, regardless.

I agree, but if supression last for 24hrs after gh administration, then it wouldnt matter when you took it. And from my personal experience, and others as well, it makes no difference in results as to when you take the gh.

 

[mt]

Problem is the reports I've seen show conflicting information. The one consistent thing is that exo gh is shown to cause supression. For how long is the question. What your natural spikes show dont have a lot of merit for me because normally when people use gh, they're getting a spike much higher than the natural gh spike.

I would like to see just one of those studies you keep referring to. Also, when referring to GH usage I'm going with replacement dosage, 2ius specifically. I don't know what a normal GH spike is. On my test it was considered pretty high. This was a natural spike. I don't know what it would have been if the spike had come from a 2iu shot.

 

[ed2005]

I agree, but if supression last for 24hrs after gh administration, then it wouldnt matter when you took it. And from my personal experience, and others as well, it makes no difference in results as to when you take the gh.

The supression will not last for 24 hours. The half life of GH is approximately 32 minutes and the whole substance should be clear of the body within 2 to 3 hours after it makes it's pass through the liver. The peak rate of natural release is during the normal night time sleep patern so by injecting before bedtime would be 'fooling' your pituitry to believe that it does not need to output any of the hormone as it would already be in existance in it's normal domain. This would obviously be undesirable as we want as much GH from our natural source as possible. However if the injection is taken during the early morning or daytime period the additional hormone will have been removed from the body by the time the individual is ready to sleep again therefore allowing the pituitry to naturally do it's job.

 

[will b huge]

The supression will not last for 24 hours. The half life of GH is approximately 32 minutes and the whole substance should be clear of the body within 2 to 3 hours after it makes it's pass through the liver. The peak rate of natural release is during the normal night time sleep patern so by injecting before bedtime would be 'fooling' your pituitry to believe that it does not need to output any of the hormone as it would already be in existance in it's normal domain. This would obviously be undesirable as we want as much GH from our natural source as possible. However if the injection is taken during the early morning or daytime period the additional hormone will have been removed from the body by the time the individual is ready to sleep again therefore allowing the pituitry to naturally do it's job.

EXACTLY what I was going to post....Simple--if you take it in the morning it will be long gone way before bed, but if you take it when you are going to sleep, then it will interupt your natural output during your first couple of hours of sleep..........

Karma to ya Ed2005.....

 

[mt]

The supression will not last for 24 hours. The half life of GH is approximately 32 minutes and the whole substance should be clear of the body within 2 to 3 hours after it makes it's pass through the liver. The peak rate of natural release is during the normal night time sleep patern so by injecting before bedtime would be 'fooling' your pituitry to believe that it does not need to output any of the hormone as it would already be in existance in it's normal domain. This would obviously be undesirable as we want as much GH from our natural source as possible. However if the injection is taken during the early morning or daytime period the additional hormone will have been removed from the body by the time the individual is ready to sleep again therefore allowing the pituitry to naturally do it's job.

This pretty coincides with everything I have read. The actual GH release is measured in minutes but the IGF growth factor is about 3 hours. I think on Ankebio's website they claim for some it can last as long as 5 hours but either way this is no where near the 24 hours the Outlaw claims. That's why I'm curious to see even one of the studies that he makes reference too.

 

[Outtlaw]

The supression will not last for 24 hours. The half life of GH is approximately 32 minutes and the whole substance should be clear of the body within 2 to 3 hours after it makes it's pass through the liver. The peak rate of natural release is during the normal night time sleep patern so by injecting before bedtime would be 'fooling' your pituitry to believe that it does not need to output any of the hormone as it would already be in existance in it's normal domain. This would obviously be undesirable as we want as much GH from our natural source as possible. However if the injection is taken during the early morning or daytime period the additional hormone will have been removed from the body by the time the individual is ready to sleep again therefore allowing the pituitry to naturally do it's job.

Just because the gh may clear the body in 3hrs, does not mean that it wont supress your natural gh longer than that. I'll try and see if I can find those studies I saw about this. In the meantime, I'd like someone to show me proof in a study that says gh does not cause supression after 3hrs time.

 

[mt]

Just because the gh may clear the body in 3hrs, does not mean that it wont supress your natural gh longer than that. I'll try and see if I can find those studies I saw about this. In the meantime, I'd like someone to show me proof in a study that says gh does not cause supression after 3hrs time.

Yes it does. If it's no longer in your body how can't it suppress you? And I already told you from personal experience: after getting a gh release from normal sleep, measured via IGF levels, I was still able to spike my gh levels above normal by dropping blood sugar via insulin approximately ten hours later. This was done in a hospital in Torrance, Little Company of Mary, with two nurses and a doctor present. The night time gh production had no suppressive effect on my natural ability to produce gh that morning.

 

[Outtlaw]

Yes it does. If it's no longer in your body how can't it suppress you?.

It can and it does. Just by you making a statement like that I can tell you dont know as much about how the body works as you think you do. When people use something as weak as anavar, their own testosterone production is suppressed after a matter of days even though the compound may no longer be acting in there body.

And I already told you from personal experience: after getting a gh release from normal sleep, measured via IGF levels, I was still able to spike my gh levels above normal by dropping blood sugar via insulin approximately ten hours later. This was done in a hospital in Torrance, Little Company of Mary, with two nurses and a doctor present. The night time gh production had no suppressive effect on my natural ability to produce gh that morning.

As I said before, your personal experience means nothing to me as you were not using exogenous gh, so your reactions cannot be applied or compared to the reactions of people who do.

 

[Outtlaw]

CLICK FOR LINK

This study shows that exogenous gh administration suppressed natural gh significantly for at least 12hrs. And after that point you can see by the graphs in figure 2 and figure 3, that natural gh production gradually began to increase, "usually" (but not in all subjects) recovering to normal levels within 24hrs.

Now, for all you experts who want to argue with me about what a controlled study says.... Post up some evidence that says otherwise.

 

[mt]

OK, so now it's 12 hours of suppression. And your implication being that if I had injected gh the night before my insulin test then there would have been no GH spike when my blood sugar was dropped by insulin. Even though your body doesn't know or care if a hormone comes from a gland or a needle. But that's because you understand how the body works. You can just tell. OK. You seem pretty hell bent on this 24 hour GH suppression thing and everyone on GH no longer produces any on their own. It's pointless to argue the point.
I can just tell.

 

[Outtlaw]

OK, so now it's 12 hours of suppression. And your implication being that if I had injected gh the night before my insulin test then there would have been no GH spike when my blood sugar was dropped by insulin. OK. You seem pretty hell bent on this 24 hour GH suppression thing and everyone on GH no longer produces any on their own. It's pointless to argue the point.

Im not saying that, because I dont know that, and neither do you. What Im saying is that you cant apply your experience when you werent taking gh, and had insulin injected into your veins for that matter in an attempt to unnaturally cause a gh spike, to what happens under normal conditions when people take gh. I dont know what you dont understand about that.

2nd, Im not saying supression last for 24hrs after gh administration (although it is possible). I said earlier that the information is conflicting and that we dont know how long the suppression last. But we do know that gh does cause suppression of your natural release. But you're saying when the gh is no longer in your system suppression cannot occur, and I posted up a study to prove you wrong. You seem to keep implying that Im way off here. And therefore I say to you again.... POST UP A STUDY TO SUPPORT YOUR CLAIMS.

I dont know how you guys can come on here and make statements without any evidence what so ever to support them. Im not saying anyones theory here is completely wrong (except for the idea that something cant be suppressive if it's no longer in the body), but before you make statements as if they are tried and proven, you'd better have some evidence to back it up.

 

[lil_tex]

So I assume after all the posts that the morning is the best time to take GH.

 

[Ulter]

Yes

 

[will b huge]

Absolutely.....

 

[ed2005]

I promised I'd get back to you Outlaw, so here's a study showing the pitfalls. I hope the originator doesn't mind.....
Cheers Ed

Lanzi R, Tannenbaum GS. Journal of Endocrinology

Department of Pediatrics, McGill University, Montreal, Quebec, Canada.

Endogenous pulsatile GH secretion is blunted by the administration of exogenous GH; however, few data are available on the time course of GH negative feedback, and the mechanism by which this occurs still remains unclear.

In the present study, we examined the temporal pattern of the inhibitory effect induced by an acute (single) and chronic (5 days) sc recombinant human (rh) GH injection regimen on spontaneous GH release in the rat and assessed the possible involvement of the hypothalamic GH-inhibitory peptide, somatostatin (SRIF), in this response. Eight-hour (0800-1600 h) GH secretory profiles, obtained from free-moving adult male rats administered a single sc injection of 200 micrograms rhGH at 0800 h, revealed a marked suppression of spontaneous GH pulses (GH peak amplitude: 45.7 +/- 10.9 vs. 207.8 +/- 31.7 ng/ml in H2O-injected control rats; P less than 0.001) lasting for up to 4.1 +/- 0.1 h after the injection (mean 4-h plasma GH level: 13.6 +/- 3.6 vs. 49.4 +/- 7.0 ng/ml in H2O-injected controls; P less than 0.01).

During the subsequent 4- to 8-h period, recovery of spontaneous GH secretory bursts was evident, and neither the GH peak amplitude nor mean 4-h plasma GH level of rhGH-treated rats was significantly different from that of H2O-injected controls. The magnitude, time course, and recovery of the rhGH-induced inhibitory effect on pulsatile GH release after chronic rhGH treatment was similar to that after a single injection.

Passive immunization of rhGH-treated rats with SRIF antiserum reversed the rhGH-induced inhibition of spontaneous GH pulses (peak amplitude: 131.7 +/- 53.7 vs. 7.1 +/- 3.4 ng/ml in rhGH-treated control rats given normal sheep serum; P less than 0.05) and restored both the GH peak amplitude and mean plasma GH level to values similar to those in H2O-injected controls.

Taken together, these results demonstrate that:
1) the inhibitory effect of rhGH on endogenous pulsatile GH release is of short duration (approximately 4 h);
2) the time course of this response does not change after 5-day repeated rhGH administration; and
3) the feedback effect of GH on its own spontaneous release is exerted, at least in part, by increasing hypothalamic SRIF secretion. Such a mechanism of GH feedback may be important in the physiological control of pulsatile GH secretion.

 

[Outtlaw]

Well Im glad somebody finally decided to post up a study to back themselves up, rather than just assuming that their word is as good as Gods simply because they said it.

I've seen that study before. One thing though, is that particular study was done on rats. And although rats are normally a good basis for human experimentation, what happens in rats does not always necessarily follow suit in humans. But it's just like I said before. There seems to be conflicting information on this subject. That study showed significant suppression for 4hrs, and significant recovery during the next 4hrs.

The study I posted showed significant suppression for 12hrs, followed by significant recovery by 18-24hrs. We really need more studies to see which is a more accurate representation of what really happens in the human body. The big question is... how long does the suppression last? The answer to that question can make a significant difference in what the best method of gh administration would be.

 

[ed2005]

Well Im glad somebody finally decided to post up a study to back themselves up, rather than just assuming that their word is as good as Gods simply because they said it.

I've seen that study before. One thing though, is that particular study was done on rats. And although rats are normally a good basis for human experimentation, what happens in rats does not always necessarily follow suit in humans. But it's just like I said before. There seems to be conflicting information on this subject. That study showed significant suppression for 4hrs, and significant recovery during the next 4hrs.

The study I posted showed significant suppression for 12hrs, followed by significant recovery by 18-24hrs. We really need more studies to see which is a more accurate representation of what really happens in the human body. The big question is... how long does the suppression last? The answer to that question can make a significant difference in what the best method of gh administration would be.

Agreed, so in the meantime I think shooting first thing a.m. will probably be the best time to ensure we best utilise our own natty release...
Cheers Bro
Ed

 

[r0nz3y]

I'm 28. I weigh 235lbs and already have above average muscle mass. I should do 5-10 IU/day? If i'm picking up Hypertropin, is that 1 vial a day?