id say alot has to due with how big you are. To me it would make sense that a 300lb, 12% male could shoot more in all areas than a 150lb, 12% male. Im 5'10, 220lbs, about 15% and ive shot up to 5cc's in my glutes. at the time i didnt know any better but had no probs. to be safe and not force the issue id say no more than 3cc's in your glutes and 2cc's all other areas. also need to beware of the products youll be shooting. for example, shooting 3 cc's of testosterone propionate may not cause any probs but it could be a fairly painful event........