I'm on my second bottle of Acnetame and it has been drying my back up and I only have a breakout every once in a while. I did have a day where I missed my doses and the next week I was battling new breakouts. I also tried to drop from 4 caps per day total (2 am, 2 pm) to 3 (2 am, 1 pm), but I get better results from 2 and 2 per day. I am pretty sure if I stop taking it, my breakouts will come back. Is it unhealthy to take for longer than a couple months at a time? WIll by body get used to it? Great product overall.