My father was a pilot for American Airlines for 31 years. Having a good reference doesn't hurt. First, you have to get your license... that will take you about 100 hours at a flight school, where you pay instructors to teach you to fly... then you need to build your hours up to about 1500 before a commercial airline will look at you...
In the mean time (after you are licensed and get your instructors license), you teach other students (thereby increaseing your hours)... once you get your commercial license then you can do charter flights for a smaller airline... around 1500 you might be able to do flights for American Eagle or types of flights like that...
My father was a Navy pilot and it took him 3 years to get into the Airlines...
C