Help!keto helps prevent t3 downreg.,too???

[leviatan]

Hi guys ( an the cunning ladies , too ...)

I am male, 26 years, about 95 kg, 9% BF, planning to get really ripped.
Diet will be ckd with carb up every other weekend at 2500 cals; i know it works good for me.

my question:

if i do:

clen (spiropent germany) 4-6 tabs a day (80-120 mcg)
ketotifen 2/3/4 g?? not really sure how much...can u tell me?
plus some gear like test prop @ 100mg eod or fina @75 mg eod

will the ketotifen only prevent downregulation of the beta- receptors or also prevent downregulation of t3 and / or decreased changing rate from t4 to t3???

would adding guggulsterone (90mg per day, syntrax guggulbolic) help withthe prob. of t3 downregulation?

bigAndy, warlobo, everyone who knows about it, please help.

thanx a lot in advance

 

[leviatan]

bump for infos...

 

[CYCLEON]

http://boards.elitefitness.com/forum/showthread.php?threadid=50676&highlight=ketotifen+clen

 

[BigAndy69]

Taurine 3-5g a day will help with T3 downregulation...Clen depletes taurine levels in the liver with suppresses conversion of T4 into T3.

It's a legal supplement, you can buy it any any supplement store.

 

[nandi12]

Studies in humans have shown that terbutaline, a beta 2 agonist like clen actually increases the T3/T4 ratio. To quote one such study:


"There was a highly significant change in the serum T3 to T4 ratio (19.4 +/- 1.0 vs. 24.4 +/- 1.0; P less than 0.001). This was a result of increased serum T3 concentrations (136 +/- 9 vs. 160 +/- 14 ng/dl; P less than 0.05) and decreased serum T4 concentrations (7.2 +/- 0.8 vs. 6.7 +/- 0.8 micrograms/dl; P = NS). Chronic beta-receptor stimulation with terbutaline sulfate increases the basal metabolic rate and T3 concentrations. These changes occurred despite down-regulation of beta-receptors and/or decreased sensitivity in response to chronic terbutaline administration." (1)

I would be VERY surprised if clen did not do the same thing, since the activity spectrum of terbutaline is virtually identical to clen.


(1) J Clin Endocrinol Metab 1984 May;58(5):895-903

Effects of chronic beta-receptor stimulation on sympathetic nervous system activity, energy expenditure, and thyroid hormones.

Scheidegger K, O'Connell M, Robbins DC, Danforth E Jr.